Haspin
Haspin is a serine/threonine-protein kinase that phosphorylates H3T3ph (histone H3 at 'Ser-3') during mitosis. It is essential for the proper cohesion, mataphase aligment and normal cell cycle progression at mitotic centromeres.
Products Related to Haspin(5)
- GC33086LDN-192960CAS: 184582-62-5Purity: >99.50%
LDN-192960 is an inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50s of 10 nM and 48 nM, respectively.
- GC44047LDN-192960 (hydrochloride)CAS: 2309172-48-1Purity: >98.00%
LDN-192960 is an inhibitor of haspin protein kinase and dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2) with IC50 values of 10 and 48 nM, respectively.
- GC50145CHR 6494 trifluoroacetateCAS: 1458630-17-5Purity: >98%
CHR 6494 trifluoroacetate is a potent inhibitor of haspin, with an IC50 of 2 nM. CHR 6494 trifluoroacetate inhibits histone H3T3 phosphorylation. CHR 6494 trifluoroacetate induces the apoptosis of cancer cells, including melanoma and breast cancer. CHR 6494 trifluoroacetate can be used in the research of cancer.
- GC69207Haspin-IN-3CAS: 2416569-95-2Purity: >98.00%
Haspin-IN-3 (compound 8l) is an effective haspin inhibitor with an IC50 of 14 nM. Haspin-IN-3 has anti-cancer properties.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC17254 | CHR-6494 | 1333377-65-3 | >98.50% | |
A selective Haspin protein kinase inhibitor | ||||
| GC33086 | LDN-192960 | 184582-62-5 | >99.50% | |
LDN-192960 is an inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50s of 10 nM and 48 nM, respectively. | ||||
| GC44047 | LDN-192960 (hydrochloride) | 2309172-48-1 | >98.00% | |
LDN-192960 is an inhibitor of haspin protein kinase and dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2) with IC50 values of 10 and 48 nM, respectively. | ||||
| GC50145 | CHR 6494 trifluoroacetate | 1458630-17-5 | >98% | |
CHR 6494 trifluoroacetate is a potent inhibitor of haspin, with an IC50 of 2 nM. CHR 6494 trifluoroacetate inhibits histone H3T3 phosphorylation. CHR 6494 trifluoroacetate induces the apoptosis of cancer cells, including melanoma and breast cancer. CHR 6494 trifluoroacetate can be used in the research of cancer. | ||||
| GC69207 | Haspin-IN-3 | 2416569-95-2 | >98.00% | |
Haspin-IN-3 (compound 8l) is an effective haspin inhibitor with an IC50 of 14 nM. Haspin-IN-3 has anti-cancer properties. | ||||