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IACS-8968 Catalog No.GC34621

Size Price Stock Qty
10mM*1mL in DMSO
$583.00
In stock
1mg
$232.00
In stock
5mg
$695.00
In stock
10mg
$1,112.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Quality Control

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Chemical Properties

Cas No. 2144425-14-7 SDF Download SDF
Synonyms N/A
Chemical Name N/A
Canonical SMILES O=C(N1)NC2(C(C)(C)CN(C3=CC(C(F)(F)F)=CC4=CN=CN34)CC2)C1=O
Formula C17H18F3N5O2 M.Wt 381.35
Solubility DMSO : 50 mg/mL (131.11 mM) Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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Background

IACS-8968 is a dual IDO and TDO inhibitor, with pIC50s of 6.43 for IDO and <5 for TDO, respectively. pIC50: 6.43 (IDO), <5 (TDO)[1].

[1]. ARYL SULFONOHYDRAZIDES. WO 2017189386 A1