GLPBio

IMB-301

Catalog No.: GC61820Purity:>99.50%
COASDSData Sheet
IMB-301 is a specific HIV-1 replication inhibitor that binds to hA3G (human APOBEC3G), interrupts the hA3G-Vif interaction and inhibits Vif-mediated degradation of hA3G.

Products are for research use only. Not for human use. We do not sell to patients.

IMB-301
Cas No.: 64009-84-3
10mM (in 1mL DMSO)In Stock
$93.00
1
1mgIn Stock
$45.00
1
5mgIn Stock
$111.00
1
10mgIn Stock
$183.00
1
25mgIn Stock
$302.00
1
50mgIn Stock
$423.00
1
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Description

IMB-301 is a HIV-1 auxilins Vif degradation hA3G antagonist. IMB-301 inhibits hA3G-Vif interactions to inhibit Vif degradations hA3G. IMB-301 has anti-HIV-1 activity[1].

IMB-301 can effectively inhibit the combination of Vif and hA3G[1].IMB 301 can be by inhibiting Vif to inhibit Vif degradations hA3G with hA3G binding specificities[1].

References:
[1]. Zhou, Jinming, et al. Applications of the IMB-301 in antiviral drugs is prepared. CN108261413A.

Product Documents

Purity:>99.50%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
64009-84-3
SMILES
FC1=CC=C(OCCC(C2=CC=C(Cl)C=C2Cl)CN3C=CN=C3)C=C1
Molecular Formula
C19H17Cl2FN2O
Molecular Weight
379.26
Solubility
DMSO : 100 mg/mL (263.67 mM; Need ultrasonic)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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