Immunosuppressants

Cyclosporin A is an immunosuppressive agent which has three major cellular targets including cyclophilins, calcineurin and transporters while it can inhibit the activity of cyclophilin A and calcineurin with an IC 50 of 360nM and 5nM.

An S1P 1 receptor agonist

Isogarcinol is a polyprenylated benzophenone natural compound extracted from plants of the Garciniagenus. Isogarcinol is also an effective inhibitor of acetylcholinesterase (AChE; IC₅₀=1.13μM) and butyrylcholinesterase (BChE; IC₅₀=8.30μM).

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.

Mycophenolic Acid β-D-Glucuronide is a metabolite of the immunosuppressant mycophenolic acid (MPA). Mycophenolic Acid β-D-Glucuronide shows anti-tumor activity and can be used in adenocarcinoma research.

21-desacetyl Deflazacort is the active glucocorticoid derived from the prodrug deflazacort.

Hydrocortisone 21-hemisuccinate is a water-soluble form of the endogenous hormone cortisol.

Leucinostatin A is a fungal metabolite originally isolated from P.

Prednisone 21-aldehyde is a derivative of the synthetic corticosteroid prednisone that has antiviral activity against influenza virus A-PR8 in embryonated chicken eggs.

7,12-Dimethylbenz[a]anthracene is an immunosuppressor as well as a potent organ-specific carcinogen.

A fungal metabolite with immunosuppressive and antitrypanosomal activities

A fungal metabolite with immunosuppressive and antiviral activities

A fungal metabolite with immunosuppressant activity

A folic acid and aminopterin derivative

An internal standard for the quantification of methotrexate

A neuropeptide with diverse biological activities

A polyketide with immunosuppressant activity

A xanthone polyketide with immunosuppressant activity

A metabolite of methotrexate

Didemnin B is a cyclic depsipeptide marine natural product with cytotoxicity.

Loliolide is a monoterpene lactone with diverse biological activities.

An internal standard for the quantification of triptolide

An internal standard for the quantification of gliotoxin

A metabolite of prednisolone