20-HEPE |
| カタログ番号GC40377 |
20-HEPEは、シトクロムP450（CYP）ω-オキシダーゼ、特に人間のCYP4F3BによるEPAのω-酸化によって形成されるエイコサペンタエン酸の代謝物です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 116477-57-7
Sample solution is provided at 25 µL, 10mM.
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20-HEPE is a metabolite of eicosapentaenoic acid that is formed via ω-oxidation of EPA by cytochrome P450 (CYP) ω-oxidases, including human CYP4F3B. It activates peroxisome proliferator-activated receptor α (PPARα) in COS-7 cells expressing a luciferase reporter when used at a concentration of 10 μM. 20-HEPE also activates murine transient receptor potential vanilloid receptor 1 (mTRPV1) in vitro but lacks antinociceptive activity in rats.
Average Rating: 5 (Based on Reviews and 23 reference(s) in Google Scholar.)
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