DSP-4 (Synonyms: Neurotoxin DSP 4 hydrochloride) |
| カタログ番号GC12042 |
DSP-4 は高度かつ選択的なアドレナリン作動性神経毒です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 40616-75-9
Sample solution is provided at 25 µL, 10mM.
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DSP-4 hydrochloride (Neurotoxin DSP 4 hydrochloride) is a highly selective neurotoxin and readily passes the blood-brain barrier with neurotoxic effects on noradrenergic neurons of adult and developing rats, can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus coeruleus (LC)[1][2].
References:
[1]. Hormigo S, et al. The selective neurotoxin DSP-4 impairs the noradrenergic projections from the locus coeruleus to the inferior colliculus in rats. Front Neural Circuits. 2012 Jun 28;6:41.
[2]. Jaim-Etcheverry G, et al. DSP-4: a novel compound with neurotoxic effects on noradrenergic neurons of adult and developing rats. Brain Res. 1980 Apr 28;188(2):513-23.
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