(E)-Flavokawain A (Synonyms: Flavokavain A, 4-methoxy Flavokawain B) |
| カタログ番号GC34981 |
カバから抽出されたカルコンである(E)-フラボカインAには、抗発がん作用があります。 (E)-フラボカイン A は、bax タンパク質依存性およびミトコンドリア依存性アポトーシス経路の関与により膀胱癌細胞のアポトーシスを誘導し、マウスの腫瘍増殖を抑制します。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 37951-13-6
Sample solution is provided at 25 µL, 10mM.
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(E)-Flavokawain A, a chalcone extracted from Kava, has anticarcinogenic effect. (E)-Flavokawain A induces apoptosis in bladder cancer cells by involvement of bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice[1].
[1]. Zi X, et al. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. Cancer Res. 2005 Apr 15;65(8):3479-86.
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