Myristic acid-d27 is intended for use as an internal standard for the quantification of myristic acid by GC- or LC-MS. Myristic acid is a 14-carbon saturated fatty acid. It is incorporated into myristoyl coenzyme A (myristoyl-CoA) and transferred by N-myristoyltransferase to the N-terminal glycine of certain proteins either during translation to modify protein activity or post-translationally in apoptotic cells.1,2
References
1. Bhatnagar, R.S., FÜtterer, K., Waksman, G., et al. The structure of myristoyl-CoA: Protein N-myristoyltransferase. Biochim. Biophys. Acta. 1441(2-3), 162-172 (1999).
2. Martin, D.D.O., Beauchamp, E., and Berthiaume, L.G. Post-translational myristoylation: Fat matters in cellular life and death. Biochimie 93(1), 18-31 (2011).