(±) Homoeriodictyol is a Aromatase/CYP19 inhibitor that can be used in breast cancer research [1].
In Vitro, (±) Homoeriodictyol (compound 5) (316.2-640×103 nM; 20 min (37 °C)) inhibits aromatase/CYP19 activity in human placental microsomes, with an IC50 of 25 μM[1].
References:
[1]. Neves MA, et al. Combining computational and biochemical studies for a rationale on the anti-aromatase activity of natural polyphenols. ChemMedChem. 2007;2(12):1750-1762.
In Vitro, (±) Homoeriodictyol (compound 5) (316.2-640×103 nM; 20 min (37 °C)) inhibits aromatase/CYP19 activity in human placental microsomes, with an IC50 of 25 μM[1].
References:
[1]. Neves MA, et al. Combining computational and biochemical studies for a rationale on the anti-aromatase activity of natural polyphenols. ChemMedChem. 2007;2(12):1750-1762.