KCC2 potentiators-1 is a KCC2 potentiator with an EC 50 of less than 0.1 μM in NG-108 cells. KCC2 potentiators-1 exhibits potentiating activity in neuronal cells via fluorescence-based assays. KCC2 potentiators-1 can be used for the research of neurological disorders [1].
In Vitro, KCC2 potentiators-1 (Compound 2) potently enhances the activity of KCC2 in NG-108 cells, with an EC50 of less than 0.1 μM[1].
References:
[1]. Joanna STANICKA, et al. Kcc2 potentiators and uses thereof. WO2024211744A1. 2025-10-05
In Vitro, KCC2 potentiators-1 (Compound 2) potently enhances the activity of KCC2 in NG-108 cells, with an EC50 of less than 0.1 μM[1].
References:
[1]. Joanna STANICKA, et al. Kcc2 potentiators and uses thereof. WO2024211744A1. 2025-10-05