M1001 |
| カタログ番号GC64945 |
M1001 は弱い低酸素誘導因子 2α (HIF-2α) アゴニストです。 M1001 は、667 nM の Kd で HIF-2α PAS-B ドメインに結合できます。 M1001 は、慢性腎臓病の研究に使用できます。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 874590-32-6
Sample solution is provided at 25 µL, 10mM.
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M1001 is a weak agonist of HIF-2α, directly binds to the HIF-2α PAS-B domain, with a Kd of 667 nM. M1001 enhances the stabilities of HIF-2α-ARNT complex[1].
[1]. Wu D, et al. Bidirectional modulation of HIF-2 activity through chemical ligands. Nat Chem Biol. 2019 Feb 25.
Review for M1001
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for M1001
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