ONO 2506 (Synonyms: ONO-2506) |
カタログ番号GC10652 |
アルンジン酸 (ONO-2506) はアストロ サイト調節剤であり、S-100β の阻害によりアストロ サイトの活性化を調節することにより、脳梗塞の拡大を遅らせます。合成。
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Cas No.: 185517-21-9
Sample solution is provided at 25 µL, 10mM.
Arundic acid (ONO-2506) is an astrocyte-modulating agent, which delays the expansion of cerebral infarcts by modulating the activation of astrocytes through inhibition of S-100β synthesis. Arundic acid (ONO-2506) has been developed as a therapeutic agent for stroke and Alzheimer’s disease[1][2][3].
References:
[1]. Tomoyuki Hasegawa, et al. Process Development of ONO-2506: A Therapeutic Agent for Stroke and Alzheimer's Disease. Org. Process Res. Dev.200372168-171.
[2]. Kato H, et al. Arundic acid, an astrocyte-modulating agent, protects dopaminergic neurons against MPTPneurotoxicity in mice. Brain Res. 2004 Dec 24;1030(1):66-73.
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