GLPBio

PROTAC Linker

Read More about this category

The PROTAC linker connects two moieties: a small peptide residue for E3 ubiquitin ligase recognition,and a ligand that can be recognized by a targeted protein.

Unlike the small molecule ligands, the length of the linker has been randomly selected for PROTACs, varying from 12-carbon to over 20-carbon in length. An optimal linker will allow for maximal interaction between the two moieties (target protein and E3 ligase) resulting in efficient ubiquitination of the target protein and its ultimate degradation.

Products Related to PROTAC Linker(2020)

  • GC73035 structure
    GC73035Mal-PEG2-oxyamine TFA
    Purity: >96.00%

    Mal-PEG2-oxyamine TFAはプロトンの合成に使用できるpegベースのprotacリンカーです。

  • GC73070 structure
    GC73070S-acetyl-PEG4-amine TFA
    Purity: >95.00%

    S-acetyl-PEG4-amine TFAはプロトンの合成に使用できるpegベースのprotacリンカーです。

  • GC73304 structure
    GC73304endo-BCN-PEG24-NHS ester
    Purity: >95.00%

    endo-BCN-PEG24-NHS esterは、ベンゾシクロノルボルネン、ポリエチレングリコール(peg)の20テトラマー、n-ドロキシスクシンイミドのエステルからなる。

  • GC74109 structure
    GC74109mPEG45-Epoxide
    CAS: 40349-67-5

    mPEG45-Epoxideはポリエーテル単位を含むPEG誘導体である。mPEG45-EpoxidePROTAC分子の合成に使用できます。

  • GC74110 structure
    GC74110mPEG45-diol
    CAS: 122202-39-5
    Purity: >97.00%

    mPEG45-diolはポリエーテル単位を含むPEG誘導体である。mPEG 45エポキシドはPROTAC分子の合成に使用できるPROTAClinkerである。

  • GC74136 structure
    GC74136Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Cbz
    CAS: 2264011-97-2
    Purity: >96.00%

    Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Cbzはprotacリンカーとmaleimide-ggfgペプチドリンカーである。

  • GC74140 structure
    GC74140Fmoc-Gly-NH-CH2-O-CH2-Cbz
    CAS: 1599440-07-9
    Purity: >95.00%

    Fmoc-Gly-NH-CH2-O-CH2-CbzはPROTAC継手とマレイミドGGFGペプチド継手である。

  • GC74143 structure
    GC74143Folate-PEG3-C2-acid
    Purity: >97.00%

    Folate-PEG3-C2-acidは、葉酸- peg3-nhsエステルの酸断片で、peg型protacリンカーに属し、protac分子の合成に用いられる。

  • GC74678 structure
    GC74678Mal-PEG3-NH2 TFA
    CAS: 2830214-77-0
    Purity: >98.00%

    Mal-PEG3-NH2 TFAは、マレイミドとアミンを含む線形のヘテロ帯電性ペグ架橋剤である。

  • GC78796 structure
    GC78796DBCO-NHCO-PEG4-amine TFA
    Purity: >96.50%

    DBCO-NHCO-PEG4-amine TFA is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

  • GC80855 structure
    GC80855Triethylene glycol-d 12
    CAS: 140196-13-0
    Purity: >98.00%

    Triethylene glycol -d 12 ( PROTAC Linker 25-d 12 ) is the deuterium labeled Triethylene glycol.

  • GC81043 structure
    GC81043Pent-4-yn-1-amine
    CAS: 15252-44-5
    Purity: >98.00%

    Pent-4-yn-1-amine is a PROTAC linker that can be used in the synthesis of PROTACs.

  • GC81044 structure
    GC810444-Aminobut-2-yn-1-ol
    CAS: 63200-68-0
    Purity: >98.00%

    4-Aminobut-2-yn-1-ol is a PROTAC linker that can be used in the synthesis of PROTACs.

  • GC81045 structure
    GC810454-Hydroxybutanal
    CAS: 25714-71-0
    Purity: >98.00%

    4-Hydroxybutanal is a PROTAC linker that can be used in the synthesis of PROTACs.

  • GC81046 structure
    GC810464-Chloro-1-butyne
    CAS: 51908-64-6
    Purity: >98.00%

    4-Chloro-1-butyne (4-Chlorobut-1-yne) is a PROTAC linker that can be used in the synthesis of PROTACs.

  • GC81047 structure
    GC810476-Amino-1-hexyne
    CAS: 15252-45-6
    Purity: >98.00%

    6-Amino-1-hexyne is a PROTAC linker that can be used in the synthesis of PROTACs.

  • GC81048 structure
    GC810485-Hydroxypentanenitrile
    CAS: 2427-16-9
    Purity: >98.00%

    5-Hydroxypentanenitrile is a PROTAC linker that can be used in the synthesis of PROTACs.

  • GC81049 structure
    GC81049N1-Methylbutane-1,4-diamine
    CAS: 14475-60-6
    Purity: >98.50%

    N1-Methylbutane-1,4-diamine is a PROTAC linker that can be used in the synthesis of PROTACs.

  • GC81050 structure
    GC810504-Chlorobutanal
    CAS: 6139-84-0
    Purity: >96.50%

    4-Chlorobutanal is a PROTAC linker that can be used in the synthesis of PROTACs.

  • GC81051 structure
    GC81051Hept-6-yn-1-amine
    CAS: 14502-42-2
    Purity: >95.00%

    Hept-6-yn-1-amine (7-Amino-1-heptyne) is a PROTAC linker that can be used in the synthesis of PROTACs.

  • GC81052 structure
    GC81052Ethyl but-3-ynoate
    CAS: 53841-07-9
    Purity: >97.50%

    Ethyl but-3-ynoate is a PROTAC linker that can be used in the synthesis of PROTACs.

  • GC81053 structure
    GC810532-(Prop-2-yn-1-yloxy)acetic acid
    CAS: 98021-61-5
    Purity: >98.00%

    2-(Prop-2-yn-1-yloxy)acetic acid is a PROTAC linker that can be used in the synthesis of PROTACs.

  • GC81054 structure
    GC810545-Oxopentanoic acid
    CAS: 5746-02-1
    Purity: >98.00%

    5-Oxopentanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.

  • GC81055 structure
    GC810555-(Methylamino)pentan-1-ol
    CAS: 2751-70-4
    Purity: >98.00%

    5-(Methylamino)pentan-1-ol is a PROTAC linker that can be used in the synthesis of PROTACs.