PROTAC Linker
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The PROTAC linker connects two moieties: a small peptide residue for E3 ubiquitin ligase recognition,and a ligand that can be recognized by a targeted protein.
Unlike the small molecule ligands, the length of the linker has been randomly selected for PROTACs, varying from 12-carbon to over 20-carbon in length. An optimal linker will allow for maximal interaction between the two moieties (target protein and E3 ligase) resulting in efficient ubiquitination of the target protein and its ultimate degradation.
Products Related to PROTAC Linker(2020)
- GC81056N1,N4-Dimethylbutane-1,4-diamineCAS: 16011-97-5Purity: >98.00%
N1,N4-Dimethylbutane-1,4-diamine is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810572-(2-Chloroethoxy)acetonitrileCAS: 31250-08-5Purity: >98.00%
2-(2-Chloroethoxy)acetonitrile is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810584-Aminobutanenitrile hydrochlorideCAS: 16011-90-8Purity: >98.00%
4-Aminobutanenitrile hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810594-EthynylcyclohexanoneCAS: 1549050-50-1Purity: >99.50%
4-Ethynylcyclohexanone is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81060Methyl 2-cyanocyclopropanecarboxylateCAS: 171055-07-5Purity: >97.00%
Methyl 2-cyanocyclopropanecarboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810617-Octynylamine (7CI,8CI)CAS: 14502-43-3Purity: >99.00%
7-Octynylamine (7CI,8CI) (7-Octyn-1-amine) is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810623-Cyanocyclobutane-1-carboxylic acidCAS: 1823933-75-0Purity: >98.00%
3-Cyanocyclobutane-1-carboxylic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81063Methyl 5-oxopentanoateCAS: 6026-86-4Purity: >98.00%
Methyl 5-oxopentanoate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810645-(Methylthio)pentan-1-amineCAS: 55021-78-8Purity: >98.00%
5-(Methylthio)pentan-1-amine is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81065Hex-5-yn-1-amine hydrochlorideCAS: 102169-54-0Purity: >98.00%
Hex-5-yn-1-amine hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81066Propargyl-PEG1-NH2 hydrochlorideCAS: 1383604-96-3Purity: >98.00%
Propargyl-PEG1-NH2 (hydrochloride) is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81067Piperazine-CH2-propargylCAS: 911398-04-4Purity: >97.50%
Piperazine-CH2-propargyl is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810683-Aminobicyclo[1.1.1]pentan-1-ol hydrochlorideCAS: 2007921-20-0Purity: >97.00%
3-Aminobicyclo[1.1.1]pentan-1-ol hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81069Ethyl hex-5-ynoateCAS: 108545-38-6Purity: >98.00%
Ethyl hex-5-ynoate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81070Non-8-yn-1-olCAS: 10160-28-8Purity: >98.00%
Non-8-yn-1-ol (8-Nonyn-1-ol) is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810712-(4-Ethynylphenyl)acetonitrileCAS: 351002-90-9Purity: >98.00%
2-(4-Ethynylphenyl)acetonitrile is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81072N1,N4-dimethylcyclohexane-1,4-diamineCAS: 2678-67-3Purity: >98.00%
N1,N4-dimethylcyclohexane-1,4-diamine is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810733-(Piperidin-4-yl)propan-1-olCAS: 7037-49-2Purity: >98.00%
3-(Piperidin-4-yl)propan-1-ol is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810744-Chlorobutan-1-amine hydrochlorideCAS: 6435-84-3Purity: >98.00%
4-Chlorobutan-1-amine hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810757-Oxoheptanoic acidCAS: 35923-65-0Purity: >98.00%
7-Oxoheptanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810761,4-CyclohexanedimethanolCAS: 105-08-8Purity: >98.00%
1,4-Cyclohexanedimethanol is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810773-(Piperazin-1-yl)propan-1-olCAS: 5317-32-8Purity: >98.00%
3-(Piperazin-1-yl)propan-1-ol is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810781-(2-Aminoethyl)piperidin-4-olCAS: 129999-60-6Purity: >98.00%
1-(2-Aminoethyl)piperidin-4-ol is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81079Methyl 6-hydroxyhexanoateCAS: 4547-43-7Purity: >98.00%
Methyl 6-hydroxyhexanoate is a PROTAC linker that can be used in the synthesis of PROTACs.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC81056 | N1,N4-Dimethylbutane-1,4-diamine | 16011-97-5 | >98.00% | |
N1,N4-Dimethylbutane-1,4-diamine is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81057 | 2-(2-Chloroethoxy)acetonitrile | 31250-08-5 | >98.00% | |
2-(2-Chloroethoxy)acetonitrile is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81058 | 4-Aminobutanenitrile hydrochloride | 16011-90-8 | >98.00% | |
4-Aminobutanenitrile hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81059 | 4-Ethynylcyclohexanone | 1549050-50-1 | >99.50% | |
4-Ethynylcyclohexanone is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81060 | Methyl 2-cyanocyclopropanecarboxylate | 171055-07-5 | >97.00% | |
Methyl 2-cyanocyclopropanecarboxylate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81061 | 7-Octynylamine (7CI,8CI) | 14502-43-3 | >99.00% | |
7-Octynylamine (7CI,8CI) (7-Octyn-1-amine) is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81062 | 3-Cyanocyclobutane-1-carboxylic acid | 1823933-75-0 | >98.00% | |
3-Cyanocyclobutane-1-carboxylic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81063 | Methyl 5-oxopentanoate | 6026-86-4 | >98.00% | |
Methyl 5-oxopentanoate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81064 | 5-(Methylthio)pentan-1-amine | 55021-78-8 | >98.00% | |
5-(Methylthio)pentan-1-amine is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81065 | Hex-5-yn-1-amine hydrochloride | 102169-54-0 | >98.00% | |
Hex-5-yn-1-amine hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81066 | Propargyl-PEG1-NH2 hydrochloride | 1383604-96-3 | >98.00% | |
Propargyl-PEG1-NH2 (hydrochloride) is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81067 | Piperazine-CH2-propargyl | 911398-04-4 | >97.50% | |
Piperazine-CH2-propargyl is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81068 | 3-Aminobicyclo[1.1.1]pentan-1-ol hydrochloride | 2007921-20-0 | >97.00% | |
3-Aminobicyclo[1.1.1]pentan-1-ol hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81069 | Ethyl hex-5-ynoate | 108545-38-6 | >98.00% | |
Ethyl hex-5-ynoate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81070 | Non-8-yn-1-ol | 10160-28-8 | >98.00% | |
Non-8-yn-1-ol (8-Nonyn-1-ol) is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81071 | 2-(4-Ethynylphenyl)acetonitrile | 351002-90-9 | >98.00% | |
2-(4-Ethynylphenyl)acetonitrile is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81072 | N1,N4-dimethylcyclohexane-1,4-diamine | 2678-67-3 | >98.00% | |
N1,N4-dimethylcyclohexane-1,4-diamine is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81073 | 3-(Piperidin-4-yl)propan-1-ol | 7037-49-2 | >98.00% | |
3-(Piperidin-4-yl)propan-1-ol is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81074 | 4-Chlorobutan-1-amine hydrochloride | 6435-84-3 | >98.00% | |
4-Chlorobutan-1-amine hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81075 | 7-Oxoheptanoic acid | 35923-65-0 | >98.00% | |
7-Oxoheptanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81076 | 1,4-Cyclohexanedimethanol | 105-08-8 | >98.00% | |
1,4-Cyclohexanedimethanol is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81077 | 3-(Piperazin-1-yl)propan-1-ol | 5317-32-8 | >98.00% | |
3-(Piperazin-1-yl)propan-1-ol is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81078 | 1-(2-Aminoethyl)piperidin-4-ol | 129999-60-6 | >98.00% | |
1-(2-Aminoethyl)piperidin-4-ol is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81079 | Methyl 6-hydroxyhexanoate | 4547-43-7 | >98.00% | |
Methyl 6-hydroxyhexanoate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||