PROTAC Linker
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The PROTAC linker connects two moieties: a small peptide residue for E3 ubiquitin ligase recognition,and a ligand that can be recognized by a targeted protein.
Unlike the small molecule ligands, the length of the linker has been randomly selected for PROTACs, varying from 12-carbon to over 20-carbon in length. An optimal linker will allow for maximal interaction between the two moieties (target protein and E3 ligase) resulting in efficient ubiquitination of the target protein and its ultimate degradation.
Products Related to PROTAC Linker(2020)
- GC81104tert-Butyl methyl(3-oxopropyl)carbamateCAS: 273757-11-2Purity: >98.00%
tert-Butyl methyl(3-oxopropyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC811055-Tert-butoxy-5-oxopentanoic acidCAS: 63128-51-8Purity: >99.50%
5-Tert-butoxy-5-oxopentanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC811062-[2-(tert-Butoxy)-2-oxoethoxy]acetic acidCAS: 120289-22-7Purity: >96.50%
2-[2-(tert-Butoxy)-2-oxoethoxy]acetic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC811071-Ethyl trans-1,4-cyclohexanedicarboxylateCAS: 15177-66-9Purity: >98.00%
1-Ethyl trans-1,4-cyclohexanedicarboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81108tert-Butyl (trans-3-(methylamino)cyclobutyl)carbamateCAS: 2168236-44-8Purity: >98.00%
tert-Butyl (trans-3-(methylamino)cyclobutyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81109Boc-Azetidine-C2-NH2CAS: 898271-20-0Purity: >97.00%
Boc-Azetidine-C2-NH2 is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81110tert-Butyl N-[3-(hydroxymethyl)cyclobutyl]carbamateCAS: 130369-05-0Purity: >98.00%
tert-Butyl N-[3-(hydroxymethyl)cyclobutyl]carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81111tert-Butyl 7-aminoheptanoateCAS: 105974-64-9Purity: >98.50%
tert-Butyl 7-aminoheptanoate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81112Tert-butyl methyl(3-(methylamino)propyl)carbamateCAS: 123183-72-2Purity: >98.00%
Tert-butyl methyl(3-(methylamino)propyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81113tert-Butyl 4-(methylamino)butylcarbamateCAS: 874831-66-0Purity: >98.50%
tert-Butyl 4-(methylamino)butylcarbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC811144-((tert-Butyldimethylsilyl)oxy)butan-1-amineCAS: 245660-15-5Purity: >98.00%
4-((tert-Butyldimethylsilyl)oxy)butan-1-amine is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC811154-Bromo-1-trimethylsilyl-1-butyneCAS: 69361-41-7Purity: >98.00%
4-Bromo-1-trimethylsilyl-1-butyne is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81116Methyl 6-aminospiro[3.3]heptane-2-carboxylate hydrochlorideCAS: 1808249-67-3Purity: >98.00%
Methyl 6-aminospiro[3.3]heptane-2-carboxylate hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81117tert-Butyl (4-chlorobutyl)carbamateCAS: 95388-79-7Purity: >98.00%
tert-Butyl (4-chlorobutyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC811184-(Benzyloxy)-4-oxobutanoic acidCAS: 103-40-2Purity: >98.00%
4-(Benzyloxy)-4-oxobutanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC811192-(4-(2-Methoxy-2-oxoethyl)phenyl)acetic acidCAS: 17833-56-6Purity: >98.00%
2-(4-(2-Methoxy-2-oxoethyl)phenyl)acetic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81120Benzyl 5-hydroxypentanoateCAS: 134848-96-7Purity: >98.00%
Benzyl 5-hydroxypentanoate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81121Methyl 5-bromo-4-oxopentanoateCAS: 53856-93-2Purity: >97.00%
Methyl 5-bromo-4-oxopentanoate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81122tert-Butyl 4-(methylamino)butanoate hydrochlorideCAS: 1246527-48-9Purity: >98.00%
tert-Butyl 4-(methylamino)butanoate hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81123Methyl 3-iodopropiolateCAS: 155004-90-3Purity: >98.00%
Methyl 3-iodopropiolate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81124Boc-2-methylamino-ethylcarbamate hydrochlorideCAS: 202207-79-2Purity: >98.00%
Boc-2-methylamino-ethylcarbamate hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC811252-(4-(Methoxycarbonyl)phenoxy)acetic acidCAS: 90812-66-1Purity: >98.00%
2-(4-(Methoxycarbonyl)phenoxy)acetic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC811263-(4-Bromophenyl)prop-2-yn-1-olCAS: 37614-58-7Purity: >98.00%
3-(4-Bromophenyl)prop-2-yn-1-ol is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC811271,4-Bis(2-chloroethyl)piperazineCAS: 1009-85-4Purity: >98.00%
1,4-Bis(2-chloroethyl)piperazine is a PROTAC linker that can be used in the synthesis of PROTACs.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC81104 | tert-Butyl methyl(3-oxopropyl)carbamate | 273757-11-2 | >98.00% | |
tert-Butyl methyl(3-oxopropyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81105 | 5-Tert-butoxy-5-oxopentanoic acid | 63128-51-8 | >99.50% | |
5-Tert-butoxy-5-oxopentanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81106 | 2-[2-(tert-Butoxy)-2-oxoethoxy]acetic acid | 120289-22-7 | >96.50% | |
2-[2-(tert-Butoxy)-2-oxoethoxy]acetic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81107 | 1-Ethyl trans-1,4-cyclohexanedicarboxylate | 15177-66-9 | >98.00% | |
1-Ethyl trans-1,4-cyclohexanedicarboxylate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81108 | tert-Butyl (trans-3-(methylamino)cyclobutyl)carbamate | 2168236-44-8 | >98.00% | |
tert-Butyl (trans-3-(methylamino)cyclobutyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81109 | Boc-Azetidine-C2-NH2 | 898271-20-0 | >97.00% | |
Boc-Azetidine-C2-NH2 is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81110 | tert-Butyl N-[3-(hydroxymethyl)cyclobutyl]carbamate | 130369-05-0 | >98.00% | |
tert-Butyl N-[3-(hydroxymethyl)cyclobutyl]carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81111 | tert-Butyl 7-aminoheptanoate | 105974-64-9 | >98.50% | |
tert-Butyl 7-aminoheptanoate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81112 | Tert-butyl methyl(3-(methylamino)propyl)carbamate | 123183-72-2 | >98.00% | |
Tert-butyl methyl(3-(methylamino)propyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81113 | tert-Butyl 4-(methylamino)butylcarbamate | 874831-66-0 | >98.50% | |
tert-Butyl 4-(methylamino)butylcarbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81114 | 4-((tert-Butyldimethylsilyl)oxy)butan-1-amine | 245660-15-5 | >98.00% | |
4-((tert-Butyldimethylsilyl)oxy)butan-1-amine is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81115 | 4-Bromo-1-trimethylsilyl-1-butyne | 69361-41-7 | >98.00% | |
4-Bromo-1-trimethylsilyl-1-butyne is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81116 | Methyl 6-aminospiro[3.3]heptane-2-carboxylate hydrochloride | 1808249-67-3 | >98.00% | |
Methyl 6-aminospiro[3.3]heptane-2-carboxylate hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81117 | tert-Butyl (4-chlorobutyl)carbamate | 95388-79-7 | >98.00% | |
tert-Butyl (4-chlorobutyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81118 | 4-(Benzyloxy)-4-oxobutanoic acid | 103-40-2 | >98.00% | |
4-(Benzyloxy)-4-oxobutanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81119 | 2-(4-(2-Methoxy-2-oxoethyl)phenyl)acetic acid | 17833-56-6 | >98.00% | |
2-(4-(2-Methoxy-2-oxoethyl)phenyl)acetic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81120 | Benzyl 5-hydroxypentanoate | 134848-96-7 | >98.00% | |
Benzyl 5-hydroxypentanoate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81121 | Methyl 5-bromo-4-oxopentanoate | 53856-93-2 | >97.00% | |
Methyl 5-bromo-4-oxopentanoate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81122 | tert-Butyl 4-(methylamino)butanoate hydrochloride | 1246527-48-9 | >98.00% | |
tert-Butyl 4-(methylamino)butanoate hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81123 | Methyl 3-iodopropiolate | 155004-90-3 | >98.00% | |
Methyl 3-iodopropiolate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81124 | Boc-2-methylamino-ethylcarbamate hydrochloride | 202207-79-2 | >98.00% | |
Boc-2-methylamino-ethylcarbamate hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81125 | 2-(4-(Methoxycarbonyl)phenoxy)acetic acid | 90812-66-1 | >98.00% | |
2-(4-(Methoxycarbonyl)phenoxy)acetic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81126 | 3-(4-Bromophenyl)prop-2-yn-1-ol | 37614-58-7 | >98.00% | |
3-(4-Bromophenyl)prop-2-yn-1-ol is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81127 | 1,4-Bis(2-chloroethyl)piperazine | 1009-85-4 | >98.00% | |
1,4-Bis(2-chloroethyl)piperazine is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||