PROTAC Linker
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The PROTAC linker connects two moieties: a small peptide residue for E3 ubiquitin ligase recognition,and a ligand that can be recognized by a targeted protein.
Unlike the small molecule ligands, the length of the linker has been randomly selected for PROTACs, varying from 12-carbon to over 20-carbon in length. An optimal linker will allow for maximal interaction between the two moieties (target protein and E3 ligase) resulting in efficient ubiquitination of the target protein and its ultimate degradation.
Products Related to PROTAC Linker(2020)
- GC81080Dec-9-yn-1-amineCAS: 1027371-95-4Purity: >99.00%
Dec-9-yn-1-amine is a PROTAC linker can be used in the synthesis of PROTACs [1] .
- GC810813-Chlorobicyclo[1.1.1]pentan-1-amine hydrochlorideCAS: 1886967-25-4Purity: >98.50%
3-Chlorobicyclo[1.1.1]pentan-1-amine hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810825-Aminopentane-1-thiol hydrochlorideCAS: 31110-78-8Purity: >99.50%
5-Aminopentane-1-thiol hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810831-(Piperidin-4-yl)azetidin-3-olCAS: 1147423-04-8Purity: >97.00%
1-(Piperidin-4-yl)azetidin-3-ol is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810841,4-Diamino-2-butyne dihydrochlorideCAS: 26232-80-4Purity: >98.00%
1,4-Diamino-2-butyne (dihydrochloride) is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810852-(4-Aminocyclohexyl)acetic acidCAS: 1197-54-2Purity: >98.00%
2-(4-Aminocyclohexyl)acetic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810869-Aminononan-1-olCAS: 109055-42-7Purity: >98.00%
9-Aminononan-1-ol (9-Amino-1-nonanol) is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81087Methyl 3-chlorobicyclo[1.1.1]pentane-1-carboxylateCAS: 156329-71-4Purity: >98.00%
Methyl 3-chlorobicyclo[1.1.1]pentane-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810886-Bromohex-1-yneCAS: 66977-99-9Purity: >98.00%
6-Bromohex-1-yne is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810894,4'-Oxybis(butan-1-ol)CAS: 3403-82-5Purity: >98.00%
4,4'-Oxybis(butan-1-ol) (Oxybisbutanol) is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810901-Azido-3-bromopropaneCAS: 153732-56-0Purity: >97.50%
1-Azido-3-bromopropane is a PROTAC linker that can be used for the synthesis of PROTACs, such as BP-198 [1] .
- GC81091Methyl 5-aminovalerate hydrochlorideCAS: 29840-56-0Purity: >98.00%
Methyl 5-aminovalerate hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810927-Methoxy-7-oxoheptanoic acidCAS: 20291-40-1Purity: >98.00%
7-Methoxy-7-oxoheptanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81093tert-Butyl 5-hydroxypentanoateCAS: 91420-49-4Purity: >98.00%
tert-Butyl 5-hydroxypentanoate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810949-Hydroxynonanoic acidCAS: 3788-56-5Purity: >98.50%
9-Hydroxynonanoic acid (omega-Hydroxynonanoic acid) is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810954-(Prop-2-yn-1-yloxy)piperidine hydrochlorideCAS: 1185100-09-7Purity: >98.00%
4-(Prop-2-yn-1-yloxy)piperidine hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810967-Azaspiro[3.5]nonan-2-ol hydrochlorideCAS: 587869-08-7Purity: >98.00%
7-Azaspiro[3.5]nonan-2-ol hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC810979-Chlorononan-1-olCAS: 51308-99-7Purity: >98.00%
9-Chlorononan-1-ol (9-Chloro-1-nonanol) is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81098Methyl 2-(4-(hydroxymethyl)phenyl)acetateCAS: 155380-11-3Purity: >98.00%
Methyl 2-(4-(hydroxymethyl)phenyl)acetate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81099(4-Bromobutyl)boronic acidCAS: 61632-72-2Purity: >98.00%
(4-Bromobutyl)boronic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81100Ethyl 2-(3-chloropropoxy)acetateCAS: 143165-48-4Purity: >98.00%
Ethyl 2-(3-chloropropoxy)acetate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81101Boc-C4-ethyneCAS: 1203588-17-3Purity: >98.00%
Boc-C4-ethyne is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC811022-[3-(Methoxycarbonyl)bicyclo[1.1.1]pentan-1-yl]acetic acidCAS: 1113001-63-0Purity: >98.00%
2-[3-(Methoxycarbonyl)bicyclo[1.1.1]pentan-1-yl]acetic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC811033-Boc-aminomethylazetidineCAS: 91188-15-7Purity: >98.00%
3-Boc-aminomethylazetidine is a PROTAC linker that can be used in the synthesis of PROTACs.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC81080 | Dec-9-yn-1-amine | 1027371-95-4 | >99.00% | |
Dec-9-yn-1-amine is a PROTAC linker can be used in the synthesis of PROTACs [1] . | ||||
| GC81081 | 3-Chlorobicyclo[1.1.1]pentan-1-amine hydrochloride | 1886967-25-4 | >98.50% | |
3-Chlorobicyclo[1.1.1]pentan-1-amine hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81082 | 5-Aminopentane-1-thiol hydrochloride | 31110-78-8 | >99.50% | |
5-Aminopentane-1-thiol hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81083 | 1-(Piperidin-4-yl)azetidin-3-ol | 1147423-04-8 | >97.00% | |
1-(Piperidin-4-yl)azetidin-3-ol is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81084 | 1,4-Diamino-2-butyne dihydrochloride | 26232-80-4 | >98.00% | |
1,4-Diamino-2-butyne (dihydrochloride) is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81085 | 2-(4-Aminocyclohexyl)acetic acid | 1197-54-2 | >98.00% | |
2-(4-Aminocyclohexyl)acetic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81086 | 9-Aminononan-1-ol | 109055-42-7 | >98.00% | |
9-Aminononan-1-ol (9-Amino-1-nonanol) is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81087 | Methyl 3-chlorobicyclo[1.1.1]pentane-1-carboxylate | 156329-71-4 | >98.00% | |
Methyl 3-chlorobicyclo[1.1.1]pentane-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81088 | 6-Bromohex-1-yne | 66977-99-9 | >98.00% | |
6-Bromohex-1-yne is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81089 | 4,4'-Oxybis(butan-1-ol) | 3403-82-5 | >98.00% | |
4,4'-Oxybis(butan-1-ol) (Oxybisbutanol) is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81090 | 1-Azido-3-bromopropane | 153732-56-0 | >97.50% | |
1-Azido-3-bromopropane is a PROTAC linker that can be used for the synthesis of PROTACs, such as BP-198 [1] . | ||||
| GC81091 | Methyl 5-aminovalerate hydrochloride | 29840-56-0 | >98.00% | |
Methyl 5-aminovalerate hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81092 | 7-Methoxy-7-oxoheptanoic acid | 20291-40-1 | >98.00% | |
7-Methoxy-7-oxoheptanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81093 | tert-Butyl 5-hydroxypentanoate | 91420-49-4 | >98.00% | |
tert-Butyl 5-hydroxypentanoate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81094 | 9-Hydroxynonanoic acid | 3788-56-5 | >98.50% | |
9-Hydroxynonanoic acid (omega-Hydroxynonanoic acid) is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81095 | 4-(Prop-2-yn-1-yloxy)piperidine hydrochloride | 1185100-09-7 | >98.00% | |
4-(Prop-2-yn-1-yloxy)piperidine hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81096 | 7-Azaspiro[3.5]nonan-2-ol hydrochloride | 587869-08-7 | >98.00% | |
7-Azaspiro[3.5]nonan-2-ol hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81097 | 9-Chlorononan-1-ol | 51308-99-7 | >98.00% | |
9-Chlorononan-1-ol (9-Chloro-1-nonanol) is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81098 | Methyl 2-(4-(hydroxymethyl)phenyl)acetate | 155380-11-3 | >98.00% | |
Methyl 2-(4-(hydroxymethyl)phenyl)acetate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81099 | (4-Bromobutyl)boronic acid | 61632-72-2 | >98.00% | |
(4-Bromobutyl)boronic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81100 | Ethyl 2-(3-chloropropoxy)acetate | 143165-48-4 | >98.00% | |
Ethyl 2-(3-chloropropoxy)acetate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81101 | Boc-C4-ethyne | 1203588-17-3 | >98.00% | |
Boc-C4-ethyne is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81102 | 2-[3-(Methoxycarbonyl)bicyclo[1.1.1]pentan-1-yl]acetic acid | 1113001-63-0 | >98.00% | |
2-[3-(Methoxycarbonyl)bicyclo[1.1.1]pentan-1-yl]acetic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81103 | 3-Boc-aminomethylazetidine | 91188-15-7 | >98.00% | |
3-Boc-aminomethylazetidine is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||