PROTAC Linker
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The PROTAC linker connects two moieties: a small peptide residue for E3 ubiquitin ligase recognition,and a ligand that can be recognized by a targeted protein.
Unlike the small molecule ligands, the length of the linker has been randomly selected for PROTACs, varying from 12-carbon to over 20-carbon in length. An optimal linker will allow for maximal interaction between the two moieties (target protein and E3 ligase) resulting in efficient ubiquitination of the target protein and its ultimate degradation.
Products Related to PROTAC Linker(2010)
- GC81162Ethyl 4-(piperazin-1-yl)benzoateCAS: 80518-57-6Purity: >98.00%
Ethyl 4-(piperazin-1-yl)benzoate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC811638-Iodooct-1-yneCAS: 60754-50-9Purity: >98.00%
8-Iodooct-1-yne is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81164Methyl 8-bromooctanoateCAS: 26825-92-3Purity: >98.00%
Methyl 8-bromooctanoate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81165Benzyl (2-(2-aminoethoxy)ethyl)carbamateCAS: 1290627-95-0Purity: >98.00%
Benzyl (2-(2-aminoethoxy)ethyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81166tert-Butyl N-{2-azaspiro[3.5]nonan-7-yl}carbamateCAS: 1434142-07-0Purity: >98.00%
tert-Butyl N-{2-azaspiro[3.5]nonan-7-yl}carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81167tert-Butyl (4-aminobicyclo[2.2.2]octan-1-yl)carbamateCAS: 1630906-54-5Purity: >98.00%
tert-Butyl (4-aminobicyclo[2.2.2]octan-1-yl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81168tert-Butyl (2-(2-aminoethoxy)ethyl)carbamate hydrochlorideCAS: 165391-09-3Purity: >98.00%
tert-Butyl (2-(2-aminoethoxy)ethyl)carbamate hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81169tert-Butyl 3-(piperazin-1-yl)azetidine-1-carboxylateCAS: 178311-48-3Purity: >98.00%
tert-Butyl 3-(piperazin-1-yl)azetidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81170Potassium (2-benzyloxyethyl)trifluoroborateCAS: 1408168-73-9Purity: >98.00%
Potassium (2-benzyloxyethyl)trifluoroborate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81171Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butanoateCAS: 1392140-97-4Purity: >98.00%
Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butanoate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81172Tert-butyl n-methyl-N-[2-(piperidin-4-yl)ethyl]carbamateCAS: 171049-32-4Purity: >98.00%
Tert-butyl n-methyl-N-[2-(piperidin-4-yl)ethyl]carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81173tert-Butyl cis-4-(2-aminoethyl)cyclohexylcarbamateCAS: 509143-12-8Purity: >98.00%
tert-Butyl cis-4-(2-aminoethyl)cyclohexylcarbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC811741-(2-(tert-Butoxy)-2-oxoethyl)piperidine-4-carboxylic acidCAS: 193903-41-2Purity: >98.00%
1-(2-(tert-Butoxy)-2-oxoethyl)piperidine-4-carboxylic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81175tert-Butyl (trans-4-hydroxymethylcyclohexylmethyl)carbamateCAS: 172348-63-9Purity: >98.00%
tert-Butyl (trans-4-hydroxymethylcyclohexylmethyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81176tert-Butyl (2-(chlorosulfonyl)ethyl)carbamateCAS: 134019-73-1Purity: >98.00%
tert-Butyl (2-(chlorosulfonyl)ethyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC811771,15-PentadecanediolCAS: 14722-40-8Purity: >98.00%
1,15-Pentadecanediol is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81178tert-Butyl 4-(2-hydroxyethoxy)piperidine-1-carboxylateCAS: 163210-40-0Purity: >98.00%
tert-Butyl 4-(2-hydroxyethoxy)piperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81179tert-Butyl N-(3-[(3-aminopropyl)(methyl)amino]propyl)carbamateCAS: 87530-14-1Purity: >98.00%
tert-Butyl N-(3-[(3-aminopropyl)(methyl)amino]propyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81180Benzyl 6-amino-2-azaspiro[3.3]heptane-2-carboxylateCAS: 1211533-81-1Purity: >97.00%
Benzyl 6-amino-2-azaspiro[3.3]heptane-2-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC811815-Bromopentan-1-amine hydrobromideCAS: 51874-27-2Purity: >96.00%
5-Bromopentan-1-amine hydrobromide is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81182Potassium succinate trihydrateCAS: 6100-18-1Purity: >98.00%
Potassium succinate trihydrate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81183cis-1-(tert-Butoxycarbonyl)-3-fluoropiperidine-4-carboxylic acidCAS: 1628475-90-0Purity: >98.00%
cis-1-(tert-Butoxycarbonyl)-3-fluoropiperidine-4-carboxylic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81184Tert-butyl (4-(aminomethyl)benzyl)(methyl)carbamateCAS: 191871-91-7Purity: >98.00%
Tert-butyl (4-(aminomethyl)benzyl)(methyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC811851-Boc-4-(Aminomethyl)piperidine hydrochlorideCAS: 359629-16-6Purity: >98.00%
1-Boc-4-(Aminomethyl)piperidine hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC81162 | Ethyl 4-(piperazin-1-yl)benzoate | 80518-57-6 | >98.00% | |
Ethyl 4-(piperazin-1-yl)benzoate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81163 | 8-Iodooct-1-yne | 60754-50-9 | >98.00% | |
8-Iodooct-1-yne is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81164 | Methyl 8-bromooctanoate | 26825-92-3 | >98.00% | |
Methyl 8-bromooctanoate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81165 | Benzyl (2-(2-aminoethoxy)ethyl)carbamate | 1290627-95-0 | >98.00% | |
Benzyl (2-(2-aminoethoxy)ethyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81166 | tert-Butyl N-{2-azaspiro[3.5]nonan-7-yl}carbamate | 1434142-07-0 | >98.00% | |
tert-Butyl N-{2-azaspiro[3.5]nonan-7-yl}carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81167 | tert-Butyl (4-aminobicyclo[2.2.2]octan-1-yl)carbamate | 1630906-54-5 | >98.00% | |
tert-Butyl (4-aminobicyclo[2.2.2]octan-1-yl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81168 | tert-Butyl (2-(2-aminoethoxy)ethyl)carbamate hydrochloride | 165391-09-3 | >98.00% | |
tert-Butyl (2-(2-aminoethoxy)ethyl)carbamate hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81169 | tert-Butyl 3-(piperazin-1-yl)azetidine-1-carboxylate | 178311-48-3 | >98.00% | |
tert-Butyl 3-(piperazin-1-yl)azetidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81170 | Potassium (2-benzyloxyethyl)trifluoroborate | 1408168-73-9 | >98.00% | |
Potassium (2-benzyloxyethyl)trifluoroborate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81171 | Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butanoate | 1392140-97-4 | >98.00% | |
Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butanoate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81172 | Tert-butyl n-methyl-N-[2-(piperidin-4-yl)ethyl]carbamate | 171049-32-4 | >98.00% | |
Tert-butyl n-methyl-N-[2-(piperidin-4-yl)ethyl]carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81173 | tert-Butyl cis-4-(2-aminoethyl)cyclohexylcarbamate | 509143-12-8 | >98.00% | |
tert-Butyl cis-4-(2-aminoethyl)cyclohexylcarbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81174 | 1-(2-(tert-Butoxy)-2-oxoethyl)piperidine-4-carboxylic acid | 193903-41-2 | >98.00% | |
1-(2-(tert-Butoxy)-2-oxoethyl)piperidine-4-carboxylic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81175 | tert-Butyl (trans-4-hydroxymethylcyclohexylmethyl)carbamate | 172348-63-9 | >98.00% | |
tert-Butyl (trans-4-hydroxymethylcyclohexylmethyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81176 | tert-Butyl (2-(chlorosulfonyl)ethyl)carbamate | 134019-73-1 | >98.00% | |
tert-Butyl (2-(chlorosulfonyl)ethyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81177 | 1,15-Pentadecanediol | 14722-40-8 | >98.00% | |
1,15-Pentadecanediol is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81178 | tert-Butyl 4-(2-hydroxyethoxy)piperidine-1-carboxylate | 163210-40-0 | >98.00% | |
tert-Butyl 4-(2-hydroxyethoxy)piperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81179 | tert-Butyl N-(3-[(3-aminopropyl)(methyl)amino]propyl)carbamate | 87530-14-1 | >98.00% | |
tert-Butyl N-(3-[(3-aminopropyl)(methyl)amino]propyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81180 | Benzyl 6-amino-2-azaspiro[3.3]heptane-2-carboxylate | 1211533-81-1 | >97.00% | |
Benzyl 6-amino-2-azaspiro[3.3]heptane-2-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81181 | 5-Bromopentan-1-amine hydrobromide | 51874-27-2 | >96.00% | |
5-Bromopentan-1-amine hydrobromide is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81182 | Potassium succinate trihydrate | 6100-18-1 | >98.00% | |
Potassium succinate trihydrate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81183 | cis-1-(tert-Butoxycarbonyl)-3-fluoropiperidine-4-carboxylic acid | 1628475-90-0 | >98.00% | |
cis-1-(tert-Butoxycarbonyl)-3-fluoropiperidine-4-carboxylic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81184 | Tert-butyl (4-(aminomethyl)benzyl)(methyl)carbamate | 191871-91-7 | >98.00% | |
Tert-butyl (4-(aminomethyl)benzyl)(methyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81185 | 1-Boc-4-(Aminomethyl)piperidine hydrochloride | 359629-16-6 | >98.00% | |
1-Boc-4-(Aminomethyl)piperidine hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||