PROTAC Linker
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The PROTAC linker connects two moieties: a small peptide residue for E3 ubiquitin ligase recognition,and a ligand that can be recognized by a targeted protein.
Unlike the small molecule ligands, the length of the linker has been randomly selected for PROTACs, varying from 12-carbon to over 20-carbon in length. An optimal linker will allow for maximal interaction between the two moieties (target protein and E3 ligase) resulting in efficient ubiquitination of the target protein and its ultimate degradation.
Products Related to PROTAC Linker(2012)
- GC81280NHBoc-PEG3-ICAS: 1801273-41-5Purity: >97.00%
NHBoc-PEG3-I is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81281tert-Butyl 17-bromoheptadecanoateCAS: 2428400-70-6Purity: >98.00%
tert-Butyl 17-bromoheptadecanoate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81282tert-Butyl 18-bromooctadecanoateCAS: 1199580-32-9Purity: >98.00%
tert-Butyl 18-bromooctadecanoate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81283Boc-PEG4-ICAS: 1291090-31-7Purity: >98.00%
Boc-PEG4-I is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC8128422-Bromodocosanoic acidCAS: 78774-39-7Purity: >98.00%
22-Bromodocosanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81285tert-Butyl 19-bromononadecanoateCAS: 2428400-73-9Purity: >98.00%
tert-Butyl 19-bromononadecanoate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81286tert-Butyl 20-bromoicosanoateCAS: 1642333-07-0Purity: >98.00%
tert-Butyl 20-bromoicosanoate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81287Ts-PEG3-O-C-alkynes-TBSCAS: 2742250-22-0Purity: >98.00%
Ts-PEG3-O-C-alkynes-TBS is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81288PEG1-bis(4,4,5,5-tetramethyl-2-phenyl-1,3,2-dioxaborolane)CAS: 957061-07-3Purity: >98.00%
PEG1-bis(4,4,5,5-tetramethyl-2-phenyl-1,3,2-dioxaborolane) is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC8128916-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]hexadecanoic acidCAS: 1356220-22-8Purity: >98.00%
16-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]hexadecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81290Fmoc-NH-PEG5-C2-NH2 hydrochloridePurity: >98.50%
Fmoc-NH-PEG5-C2-NH2 hydrochloride is a PEG-based PROTAC linker.
- GC81291BG-PEG4-AminePurity: >98.00%
BG-PEG4-Amine is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81292BG-PEG8-AminePurity: >98.00%
BG-PEG8-Amine is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81293DBCO-PEG5-GGG-NH2CAS: 2762519-06-0Purity: >95.50%
DBCO-PEG5-GGG-NH2 is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81294BG-PEG4-DBCOPurity: >98.00%
BG-PEG4-DBCO is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81295DBCO-PEG9-amine TFAPurity: >97.50%
DBCO-PEG9-amine (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- GC8152317-Bromoheptadecanoic acidCAS: 13099-35-9Purity: >98.00%
17-Bromoheptadecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC818668-Azidooctan-1-amineCAS: 867338-63-4Purity: >98.00%
8-Azidooctan-1-amine is a PROTAC linker that can be used in PROTAC synthesis-related research, such as L013 [1] .
- GD143381,7-HeptanediolCAS: 629-30-1Purity: >99.50%
1,7-Heptanediolは、E3ユビキチンリガーゼリガンドと標的タンパク質リガンドを連結するPROTACリンカーとして機能する。
- GF04904PC DBCO-PEG4-NHS esterCAS: 2055025-02-8Purity: >98.00%
PC DBCO-PEG4-NHSエステル（PC DBCO-PEG4-NHS ester）はPEGに基づいたPROTACリンカーであり、PROTAC分子の合成のためのクリック化学ではリンカーとして使われることができる。
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC81280 | NHBoc-PEG3-I | 1801273-41-5 | >97.00% | |
NHBoc-PEG3-I is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81281 | tert-Butyl 17-bromoheptadecanoate | 2428400-70-6 | >98.00% | |
tert-Butyl 17-bromoheptadecanoate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81282 | tert-Butyl 18-bromooctadecanoate | 1199580-32-9 | >98.00% | |
tert-Butyl 18-bromooctadecanoate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81283 | Boc-PEG4-I | 1291090-31-7 | >98.00% | |
Boc-PEG4-I is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81284 | 22-Bromodocosanoic acid | 78774-39-7 | >98.00% | |
22-Bromodocosanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81285 | tert-Butyl 19-bromononadecanoate | 2428400-73-9 | >98.00% | |
tert-Butyl 19-bromononadecanoate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81286 | tert-Butyl 20-bromoicosanoate | 1642333-07-0 | >98.00% | |
tert-Butyl 20-bromoicosanoate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81287 | Ts-PEG3-O-C-alkynes-TBS | 2742250-22-0 | >98.00% | |
Ts-PEG3-O-C-alkynes-TBS is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81288 | PEG1-bis(4,4,5,5-tetramethyl-2-phenyl-1,3,2-dioxaborolane) | 957061-07-3 | >98.00% | |
PEG1-bis(4,4,5,5-tetramethyl-2-phenyl-1,3,2-dioxaborolane) is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81289 | 16-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]hexadecanoic acid | 1356220-22-8 | >98.00% | |
16-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]hexadecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81290 | Fmoc-NH-PEG5-C2-NH2 hydrochloride | - | >98.50% | |
Fmoc-NH-PEG5-C2-NH2 hydrochloride is a PEG-based PROTAC linker. | ||||
| GC81291 | BG-PEG4-Amine | - | >98.00% | |
BG-PEG4-Amine is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81292 | BG-PEG8-Amine | - | >98.00% | |
BG-PEG8-Amine is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81293 | DBCO-PEG5-GGG-NH2 | 2762519-06-0 | >95.50% | |
DBCO-PEG5-GGG-NH2 is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81294 | BG-PEG4-DBCO | - | >98.00% | |
BG-PEG4-DBCO is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81295 | DBCO-PEG9-amine TFA | - | >97.50% | |
DBCO-PEG9-amine (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81523 | 17-Bromoheptadecanoic acid | 13099-35-9 | >98.00% | |
17-Bromoheptadecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81866 | 8-Azidooctan-1-amine | 867338-63-4 | >98.00% | |
8-Azidooctan-1-amine is a PROTAC linker that can be used in PROTAC synthesis-related research, such as L013 [1] . | ||||
| GD14338 | 1,7-Heptanediol | 629-30-1 | >99.50% | |
1,7-Heptanediolは、E3ユビキチンリガーゼリガンドと標的タンパク質リガンドを連結するPROTACリンカーとして機能する。 | ||||
| GF04904 | PC DBCO-PEG4-NHS ester | 2055025-02-8 | >98.00% | |
PC DBCO-PEG4-NHSエステル（PC DBCO-PEG4-NHS ester）はPEGに基づいたPROTACリンカーであり、PROTAC分子の合成のためのクリック化学ではリンカーとして使われることができる。 | ||||