Sigvotatug (SGN-B6A antibody) is a human IgG1 κ monoclonal antibody against ITGB6. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control. Sigvotatug can be used as an ADC antibody to synthesize ADC Sigvotatug vedotin [1].
In Vitro, Sigvotatug vedotin (SGN-B6A) is an ADC molecule with anti-tumor activity[1].
References:
[1]. Lyon RP, et al. SGN-B6A: A New Vedotin Antibody-Drug Conjugate Directed to Integrin Beta-6 for Multiple Carcinoma Indications. Mol Cancer Ther. 2023 Dec 1;22(12):1444-1453.
In Vitro, Sigvotatug vedotin (SGN-B6A) is an ADC molecule with anti-tumor activity[1].
References:
[1]. Lyon RP, et al. SGN-B6A: A New Vedotin Antibody-Drug Conjugate Directed to Integrin Beta-6 for Multiple Carcinoma Indications. Mol Cancer Ther. 2023 Dec 1;22(12):1444-1453.