GLPBio

STAT6-IN-10

Catalog No.: GC79469Purity:>98.50%
COASDSData Sheet
STAT6-IN-10 is a STAT6 (signal transducer and activator of transcription 6) inhibitor with an EC 50 of 2 nM.

製品は研究用途にのみ使用できます。人体には使用できません。患者への販売は行っておりません。

STAT6-IN-10
Cas No.: 3092076-19-9
10mM (in 1mL DMSO)In Stock
$629.00
1
1mgIn Stock
$225.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

引用文献 (Citations)

現在、この製品の引用文献はありません。以下はGlpBio製品を引用した代表的な文献です。
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

製品説明 (Description)

STAT6-IN-10 is a STAT6 (signal transducer and activator of transcription 6) inhibitor with an EC 50 of 2 nM. STAT6-IN-10 can inhibit the secretion of CCL17 in human peripheral whole blood. STAT6-IN-10 can be used in the research of dermatological and respiratory system diseases [1].

In Vitro, STAT6-IN-10 (Example 10) can inhibit the secretion of CCL17 in human peripheral whole blood, and its IC50 is 0.095 μM[1].

References:
[1]. Chulho Cho, et al. Nitrogen-containing heteroaryl compounds for the treatment of chronic disease. WO2025133961. 2025-06-26.

製品資料 (Product Documents)

Purity:>98.50%Appearance:A solid
COASDSData Sheet

化学的性質 (Chemical Properties)

CAS番号
3092076-19-9
分子式
C29H29N7O2
分子量
507.59
溶解性
DMSO: 25 mg/mL (49.25 mM; Need ultrasonic)
保存条件
Store at -20°C
配送条件
評価用サンプルは保冷剤とともに発送します。その他の容量は室温で発送し、ご要望に応じて保冷剤を同梱します。

計算ツール (Calculators)モル濃度 / 希釈 / 分子量 / 単位変換 / in vivo製剤 / 溶解度

g/mol

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