GLPBio

Toliprolol

Catalog No.: GC79265Purity:>99.50%
COASDSData Sheet
Toliprolol is a β 1 /β 2 -selective β- adrenergic Receptor antagonist.

製品は研究用途にのみ使用できます。人体には使用できません。患者への販売は行っておりません。

Toliprolol
Cas No.: 2933-94-0
10mM (in 1mL DMSO)In Stock
$530.00
1
1mgIn Stock
$194.00
1
5mgIn Stock
$482.00
1
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引用文献 (Citations)

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    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

製品説明 (Description)

Toliprolol is a β 1 /β 2 -selective β- adrenergic Receptor antagonist. Toliprolol is used in the research of angina pectoris and hypertension [1].

In Vitro, Toliprolol (Compound 4d) acts as a β1-adrenergic receptor antagonist in isolated guinea pig left atria, with a pA2 value of 8.75[1]. Toliprolol acts as a β2-adrenergic receptor antagonist in isolated guinea pig tracheal chains, with a pA2 value of 7.94 and a β1/β2 selectivity ratio of 6.5[1].

References:
[1]. Mauleón D, et al. Synthesis and beta-adrenergic antagonism of 2-(aryloxy)-1-(2-piperidyl)ethanols. J Med Chem. 1988;31(11):2122-2126.

製品資料 (Product Documents)

Purity:>99.50%Appearance:A solid
COASDSData Sheet

化学的性質 (Chemical Properties)

CAS番号
2933-94-0
分子式
C13H21NO2
分子量
223.31
溶解性
DMSO: ≥ 100 mg/mL (447.81 mM)
保存条件
Store at -20°C
配送条件
評価用サンプルは保冷剤とともに発送します。その他の容量は室温で発送し、ご要望に応じて保冷剤を同梱します。

計算ツール (Calculators)モル濃度 / 希釈 / 分子量 / 単位変換 / in vivo製剤 / 溶解度

g/mol

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