GLPBio

ZEN-3862

Catalog No.: GC84451Purity:>95.00%
COASDSData Sheet
ZEN-3862 is a BET inhibitor with IC50 s of 0.16 and 0.13 μM for BRD4 (BD1) and BRD4 (BD2), respectively.

製品は研究用途にのみ使用できます。人体には使用できません。患者への販売は行っておりません。

ZEN-3862
Cas No.: 1952264-33-3
10mM (in 1mL DMSO)In Stock
$91.00
1
1mgIn Stock
$38.00
1
5mgIn Stock
$83.00
1
10mgIn Stock
$126.00
1
25mgIn Stock
$225.00
1
50mgIn Stock
$295.00
1
100mgIn Stock
$404.00
1
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引用文献 (Citations)

現在、この製品の引用文献はありません。以下はGlpBio製品を引用した代表的な文献です。
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

製品説明 (Description)

ZEN-3862 is a BET inhibitor with IC50 s of 0.16 and 0.13 μM for BRD4 (BD1) and BRD4 (BD2), respectively. ZEN-3862 can be used to form PROTAC s to induce degradation of BRD4 [1].

References:
[1]. Kharenko OA, et al. Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine. J Med Chem. 2018 Sep 27;61(18):8202-8211.

製品資料 (Product Documents)

Purity:>95.00%Appearance:A solid
COASDSData Sheet

化学的性質 (Chemical Properties)

CAS番号
1952264-33-3
分子式
C19H17FN2O3
分子量
340.35
溶解性
DMSO: 83.33 mg/mL (244.84 mM; Need ultrasonic)
保存条件
Store at -20°C
配送条件
評価用サンプルは保冷剤とともに発送します。その他の容量は室温で発送し、ご要望に応じて保冷剤を同梱します。

計算ツール (Calculators)モル濃度 / 希釈 / 分子量 / 単位変換 / in vivo製剤 / 溶解度

g/mol

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