GLPBio

KAT modulator-1

Catalog No.: GC73483Purity:>98.00%
COASDSData Sheet
KAT modulator-1 (Compound 3) is a KAT modulator.

Products are for research use only. Not for human use. We do not sell to patients.

KAT modulator-1
Cas No.: 1314006-43-3
1 mgIn Stock
$63.00
1
5 mgIn Stock
$142.00
1
10 mgIn Stock
$228.00
1
25 mgIn Stock
$455.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

KAT modulator-1 (Compound 3) is a KAT modulator. KAT modulator-1 can interact with p300 full-length but not with the catalytic domain. KAT modulator-1 can be used for epigenetics research.

KAT modulator-1 (Compound 3) (50 μM) inhibits recombinant acetyltransferase enzymes KAT3A by 79-83%[1].KAT modulator-1 (15 and 30 μM) reduces H3 acetylation in histone extracts of U937 leukemia cells[1].

References:
[1]. Milite C, et al. Modulation of the activity of histone acetyltransferases by long chain alkylidenemalonates (LoCAMs). Bioorg Med Chem. 2011 Jun 15;19(12):3690-701.

Product Documents

Purity:>98.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
1314006-43-3
Molecular Formula
C20H36O2
Molecular Weight
308.5
Solubility
DMSO : 100 mg/mL (324.15 mM; ultrasonic and warming and heat to 80°C)
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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