GLPBio

KL044

Catalog No.: GC63033Purity:>99.00%
COASDSData Sheet
KL044, a stabilizer of the clock protein cryptochrome (CRY) , is a potent chemical probe with a pEC50 value of 7.32, leading to the extension of the circadian period and repression of Per2 activity.

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KL044
Cas No.: 1801856-93-8
5 mgIn Stock
$225.00
1
10 mgIn Stock
$405.00
1
25 mgIn Stock
$765.00
1
50 mgIn Stock
$1,215.00
1
100 mgIn Stock
$1,755.00
1
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Description

KL044, a stabilizer of the clock protein cryptochrome (CRY) , is a potent chemical probe with a pEC50 value of 7.32, leading to the extension of the circadian period and repression of Per2 activity[1].

KL044 (0-3.7 μM; 8 h) effectively stabilizes the CRY1-LUC fusion protein without affecting the stability of LUC in the HEK293 stable cell line[1].

[1]. Jae Wook Lee, et al. Development of Small-Molecule Cryptochrome Stabilizer Derivatives as Modulators of the Circadian Clock. ChemMedChem. 2015 Sep;10(9):1489-97.

Product Documents

Purity:>99.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
1801856-93-8
Molecular Formula
C21H14ClN3O
Molecular Weight
359.81
Solubility
DMSO : 100 mg/mL (277.92 mM; Need ultrasonic)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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