>>Signaling Pathways>> Immunology/Inflammation>> Apoptosis>>(1S)-PMMB276

(1S)-PMMB276

Catalog No.GC78937 Copy One-Click Copy Product Info

(1S)-PMMB276 is the (1S)-enantiomer of PMMB276.

Products are for research use only. Not for human use. We do not sell to patients.

(1S)-PMMB276 Chemical Structure

Size 가격 재고 수량
5mg
US$146.00
재고 있음
10mg
US$241.00
재고 있음

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고객 리뷰

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of (1S)-PMMB276

(1S)-PMMB276 is the (1S)-enantiomer of PMMB276. PMMB276 is a potent inhibitor of β-tubulin isotype III (Tubb3) polymerization and induced apoptosis [1].

References:
[1]. Hongwei Han, et al. A modified natural small molecule inhibits triple-negative breast cancer growth by interacting with Tubb3. Phytomedicine. 2024 Apr:126:154894.

Chemical Properties of (1S)-PMMB276

Cas No. SDF
Formula C31H34O6S2 M.Wt 566.73
Solubility DMSO: 50 mg/mL (88.23 mM; Need ultrasonic) Storage Store at -20°C
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of (1S)-PMMB276

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.7645 mL 8.8225 mL 17.6451 mL
5 mM 352.9 μL 1.7645 mL 3.529 mL
10 mM 176.5 μL 882.3 μL 1.7645 mL
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In vivo Formulation Calculator (Clear solution) of (1S)-PMMB276

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for (1S)-PMMB276

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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