Anti-Mouse CXCL10 Antibody (1F11) is a mouse CXCL10 antibody. Anti-Mouse CXCL10 Antibody (1F11) blocks the activity of CXCL10 and inhibits GPCR -dependent interstitial motility of Th1 cells in inflamed dermis. Anti-Mouse CXCL10 Antibody (1F11) can be used for research on inflammation-related diseases. Recommended isotype control: Polyclonal Armenian hamster IgG, Isotype Control [1].
In Vivo, Anti-mouse CXCL10 antibody (1F11) (500 µg; i.v.; single dose) selectively impairs Th1 cell interstitial motility in the inflamed murine dermis, with no effect on Th2 cell motility[1].
References:
[1]. Gaylo-Moynihan A, et al. Programming of Distinct Chemokine-Dependent and -Independent Search Strategies for Th1 and Th2 Cells Optimizes Function at Inflamed Sites. Immunity. 2019 Aug 20;51(2):298-309.e6.
In Vivo, Anti-mouse CXCL10 antibody (1F11) (500 µg; i.v.; single dose) selectively impairs Th1 cell interstitial motility in the inflamed murine dermis, with no effect on Th2 cell motility[1].
References:
[1]. Gaylo-Moynihan A, et al. Programming of Distinct Chemokine-Dependent and -Independent Search Strategies for Th1 and Th2 Cells Optimizes Function at Inflamed Sites. Immunity. 2019 Aug 20;51(2):298-309.e6.