CMP233 is a potent antagonist of TRPM4, with the IC50 of 0.15 μM. CMP233 plays an important role in neurodegenerative disorders research [1].
References:
[1]. Lars Binkle-Ladisch, et al. Identification and development of TRPM4 antagonists to counteract neuronal excitotoxicity. iScience. 2024 Nov 19;27(12):111425.
References:
[1]. Lars Binkle-Ladisch, et al. Identification and development of TRPM4 antagonists to counteract neuronal excitotoxicity. iScience. 2024 Nov 19;27(12):111425.
















