GLPBio

Drug Metabolite

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Products Related to Drug Metabolite(546)

  • GC10822 structure
    GC10822Clozapine N-oxide (CNO)
    CAS: 34233-69-7
    Purity: >98.00%

    Clozapine N-oxide (CNO)는 화학유전학 연구에서 사용되는 DREADD 시스템의 리간드이다.

  • GC11155 structure
    GC11155Omeprazole sulfone
    CAS: 88546-55-8
    Purity: >98%

    오메프라졸 설폰은 양성자 펌프 억제제인 오메프라졸의 대사 산물입니다.

  • GC11989 structure
    GC11989Nortriptyline (hydrochloride)
    CAS: 894-71-3
    Purity: >99.50%

    Amitriptyline의 주요 활성 대사산물인 Nortriptyline(염산염)(Desmethylamitriptyline hydrochloride)은 우울증 증상을 완화하는 데 사용되는 삼환계 항우울제입니다.

  • GC12685 structure
    GC12685Ercalcitriol
    CAS: 60133-18-8
    Purity: >99.00%

    A potent agonist of the vitamin D receptor

  • GC14762 structure
    GC14762Palifosfamide
    CAS: 31645-39-3
    Purity: >98%

    An active metabolite of ifosfamide

  • GC14780 structure
    GC14780Oseltamivir acid
    CAS: 187227-45-8
    Purity: >98.00%

    A neuraminidase inhibitor and antiviral

  • GC15168 structure
    GC15168Urolithin A
    CAS: 1143-70-0
    Purity: >98.50%

    Urolithin A는 엘라그산과 엘라그탄닌에서 생성된 대사 산물로 티로시나아제 (IC 50 값 71.44±10.07 μmol/L)와 모노아민 산화효소 A (IC50 값 29.41±9.01 μmol/L)의 강력한 억제제이다.

  • GC16292 structure
    GC16292Equol
    CAS: 94105-90-5
    Purity: >98.00%

    Equol은 equol의 라세미체입니다.

  • GC16333 structure
    GC16333Cycloguanil (hydrochloride)
    CAS: 152-53-4
    Purity: >99.50%

    Proguanil의 활성 대사 산물인 Cycloguanil(염산염)은 적혈구와 간세포의 말라리아 분열에 작용합니다.

  • GC16553 structure
    GC16553N-Desmethylclozapine
    CAS: 6104-71-8
    Purity: >99.50%

    N-데스메틸클로자핀은 비정형 항정신병 약물 클로자핀의 주요 활성 대사산물입니다.

  • GC18194 structure
    GC181944-Epidoxycycline
    CAS: 6543-77-7
    Purity: >98%

    4-Epidoxycycline is the 4-epimer hepatic metabolite of the antibiotic doxycycline .

  • GC18219 structure
    GC182196-hydroxy Warfarin
    CAS: 17834-02-5
    Purity: >98.00%

    6-hydroxy Warfarin is a metabolite of (+)-warfarin , which is a weaker vitamin K antagonist than (-)-warfarin .

  • GC18335 structure
    GC183356β-hydroxy Dexamethasone
    CAS: 55879-47-5
    Purity: >98%

    6β-hydroxy Dexamethasone is a metabolite of dexamethasone that is more hydrophilic than the parent compound.

  • GC18417 structure
    GC184174-hydroxy Xylazine
    CAS: 145356-32-7
    Purity: >97.50%

    4-하이드록시 실라진은 실라진의 대사산물입니다.

  • GC18425 structure
    GC184254-hydroxy Atorvastatin lactone
    CAS: 163217-70-7
    Purity: >98%

    4-hydroxy Atorvastatin lactone is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.

  • GC18439 structure
    GC18439Doxorubicinone
    CAS: 24385-10-2
    Purity: >95.00%

    독소루비시논은 항암 화학요법제 독소루비신의 대사 산물입니다. 독소루비신은 IC50이 각각 0.8μM 및 2.67μM인 강력한 인간 DNA 토포이소머라제 I 및 토포이소머라제 II 억제제입니다.

  • GC18455 structure
    GC18455Digoxigenin Monodigitoxoside
    CAS: 5352-63-6
    Purity: >98%

    디곡시제닌 모노디지톡소사이드는 Na+/K+ ATPase 억제제이자 디곡신의 심장 배당체 대사 산물입니다.

  • GC18466 structure
    GC184665,6-epoxy-13-cis Retinoic Acid
    CAS: 81444-57-7
    Purity: >98%

    5,6-epoxy-13-cis Retinoic acid is a metabolite of 13-cis retinoic acid.

  • GC18527 structure
    GC185274'-hydroxy Flurbiprofen
    CAS: 52807-12-2
    Purity: >98%

    A major active metabolite of flurbiprofen

  • GC18539 structure
    GC185394-Hydroxyretinoic acid (4-HRA)
    CAS: 66592-72-1
    Purity: >98.00%

    4-Hydroxyretinoic acid (4-HRA)은 사이토크롬 P450 효소 대사를 통해 전트랜스 레티노산(ATRA)에서 유래하는 천연 발생성 1차 대사 산물이다.

  • GC18542 structure
    GC185425,6-dihydro-5-Fluorouracil
    CAS: 696-06-0
    Purity: >95.00%

    5,6-dihydro-5-Fluorouracil (5-FUH2) is formed by the hydrogenation of 5-fluorouracil via the enzyme dihydropyrimidine dehydrogenase (DPD).

  • GC18569 structure
    GC18569Propofol β-D-Glucuronide
    CAS: 114991-26-3
    Purity: >98.00%

    Propofol β-D-Glucuronide는 프로포폴의 대사산물로서 동물 체내 프로포폴 대사 상태를 판단하는 지표로 일반적으로 사용된다.

  • GC18582 structure
    GC185825'-hydroxy Meloxicam
    CAS: 130262-92-9
    Purity: >98%

    A metabolite of meloxicam

  • GC18596 structure
    GC18596(±)-2-propyl-4-Pentenoic Acid
    CAS: 1575-72-0
    Purity: >98.00%

    (±)-2-프로필-4-펜텐산(4-en-VPA)은 발프로산의 주요 독성 대사산물입니다.