Fenpropathrin is a pyrethroid insecticide.1 It is a slow activator of voltage-gated sodium channel 1.8 (Nav1.8). Fenpropathrin induces mortality in the two-spotted spider mite (T. urticae) with an LC50 value of 2.35 g AI/L in a slide-dip assay.2 It has been found in watershed sediment samples.3 Formulations containing fenpropathrin have been used as insecticides in agriculture.
1.Choi, J.S., and Soderlund, D.M.Structure-activity relationships for the action of 11 pyrethroid insecticides on rat Nav1.8 sodium channels expressed in Xenopus oocytesToxicol. Appl. Pharmacol.211(3)233-244(2006) 2.Penman, D.R., Chapman, R.B., and Bowie, M.H.Direct toxicity and repellent activity of pyrethroids against Tetranychus urticae (Acari: Tetranychidae)J. Econ. Entomol.79(5)1183-1187(1986) 3.Budd, R., Bondarenko, S., Haver, D., et al.Occurrence and bioavailability of pyrethroids in a mixed land use watershedEnviron. Qual.36(4)1006-1012(2007)