>>Signaling Pathways>> Immunology/Inflammation>> NF-κB>>Licochalcone D

Licochalcone D

Catalog No.GC36446

Glycyrrhiza inflate의 뿌리에 주로 존재하는 플라보노이드 화합물인 Licochalcone D는 NF-kappaB(NF-κB) p65의 강력하고 경구 활성 억제제입니다.

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Licochalcone D Chemical Structure

Cas No.: 144506-15-0

Size 가격 재고 수량
1mg
US$210.00
재고 있음
5mg
US$380.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Licochalcone D, a flavonoid compound mainly existing in the root of Glycyrrhiza inflate, is a potent inhibitor of NF-kappaB (NF-κB) p65. Licochalcone D possesses antioxidant, anti-inflammatory, anti-cancer properties[1][2]. p65

[1]. Furusawa J, et al. Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-kappaB p65 in LPS signaling pathway. Int Immunopharmacol. 2009 Apr;9(4):499-507. [2]. Si L, et al. Licochalcone D induces apoptosis and inhibits migration and invasion in human melanoma A375 cells. Oncol Rep. 2018 May;39(5):2160-2170.

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