Thalidomide-O-amido-C3-NH2 (TFA) (Synonyms: Cereblon Ligand-Linker Conjugates 16 TFA; E3 Ligase Ligand-Linker Conjugates 52 TFA) |
| Catalog No.GC38095 |
탈리도마이드-O-아미도-C3-NH2(TFA)는 탈리도마이드 기반 세레블론 리간드와 PROTAC 기술에 사용되는 링커를 통합하는 합성된 E3 리가제 리간드-링커 접합체입니다.
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Cas No.: 2022182-58-5
Sample solution is provided at 25 µL, 10mM.
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Thalidomide-O-amido-C3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
[1]. Lohbeck J, et al. Practical synthesis of a phthalimide-based Cereblon ligand to enable PROTAC development. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5260-5262.
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