Poricoic acid A |
| Catalog No.GC36948 |
Poria cocos에서 분리된 Poricoic acid A는 항종양 활성을 가지고 있습니다. 포리코산 A는 Gas6/AxlNFκB/Nrf2 축을 조절하여 AKI에서 CKD로의 전이를 억제하는 멜라토닌을 향상시킵니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 137551-38-3
Sample solution is provided at 25 µL, 10mM.
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Poricoic acid A, isolated from Poria cocos, possesses anti-tumor activity[1]. Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis[2].
[1]. Dong H, et al. Enrichment and separation of antitumor triterpene acids from the epidermis of Poria cocos by pH-zone-refining counter-current chromatography and conventional high-speed counter-current chromatography. J Sep Sci. 2015 Jun;38(11):1977-82. [2]. Chen DQ, et al. Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis. Free Radic Biol Med. 2019 Apr;134:484-497.
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