2'-O-Methyladenosine-5'-Triphosphate is an ATP analog which is methylated at the 2'-O position of the ribose sugar. Methylation at this position results in increased stability of the resulting RNA strand against base hydrolysis and nuclease cleavage. This makes it a useful NTP for aptamer synthesis where increased variation in nucleotide composition along with increased nuclease resistance are desired.
인용 문헌 (Citations)
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제품 문서 (Product Documents)
Purity:>95.00%
화학적 특성 (Chemical Properties)
순도
>95.00%
흡광 계수
15,400 Lmol-1cm-1 at 258 nm
분자식
C11H18N5O13P3 (free acid)
M.Wt
521.20 g/mole (free acid)
염 형태
Li+
농도
100 mM
완충액
H2O
보관
-20°C or below
동의어
2'-O-Methyl-ATP
백본
5'-Triphosphate
염기 유사체
Adenosine
당 유형
2'-O-Methyl
뉴클레오타이드 분류
Sugar Modified
응용 분야
Aptamers, Epigenetics/DNA Damage
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