GPR109A
GPR109A (also known as hydroxycarboxylic acid receptor 2) is a nicotinic acid/niacin and (D)-beta-hydroxybutyrate receptor. It conveys acid-induced apoptosis in matureneutrophils and may lead to neutrophilapoptosis after niacin activation.
Products Related to GPR109A(4)
- GC15653PF-05212384 (PKI-587)CAS: 1197160-78-3Purity: >98.00%
PF-05212384 (PKI-587)는 강력한 이중 PI3K/mTOR 억제제로 PI3Kα(IC₅₀=0.4 nM), PI3Kβ(IC₅₀=6 nM), PI3Kγ(IC₅₀=8 nM), PI3Kδ(IC₅₀=6 nM) 및 mTOR(IC₅₀=1.4 nM)에 대해 억제 활성을 나타낸다.
- GC74667GPR109 receptor agonist-2CAS: 957129-38-3Purity: >99.00%
GPR109 receptor agonist-2 (화합물 5)는 선택적 GPR109a 흥분제로서 pEC50은 5.53입니다.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC15653 | PF-05212384 (PKI-587) | 1197160-78-3 | >98.00% | |
PF-05212384 (PKI-587)는 강력한 이중 PI3K/mTOR 억제제로 PI3Kα(IC₅₀=0.4 nM), PI3Kβ(IC₅₀=6 nM), PI3Kγ(IC₅₀=8 nM), PI3Kδ(IC₅₀=6 nM) 및 mTOR(IC₅₀=1.4 nM)에 대해 억제 활성을 나타낸다. | ||||
| GC15006 | MK-6892 | 917910-45-3 | >99.00% | |
| GC32464 | MK-0354 | 851776-28-8 | >99.00% | |
MK-0354는 GPR109a 수용체의 부분 작용제이며, EC50이 1.65/1.08 μM인 hGPR109a/mGPR109a에 대해 GPR109b의 활성화를 나타내지 않았습니다. | ||||
| GC74667 | GPR109 receptor agonist-2 | 957129-38-3 | >99.00% | |
GPR109 receptor agonist-2 (화합물 5)는 선택적 GPR109a 흥분제로서 pEC50은 5.53입니다. | ||||