GLPBio

GSPT1 degrader-15

Catalog No.: GC81688Purity:>95.00%
COASDSData Sheet
GSPT1 degrader-15 (Compound Lib-B-15O) is a potent and highly selective GSPT1 molecular gel degrader, with a DC50 of 154 nM.

제품은 연구용으로만 사용됩니다. 인체에 사용할 수 없으며 환자에게 판매하지 않습니다.

GSPT1 degrader-15
Cas No.: 3060504-66-4
10mM (in 1mL DMSO)In Stock
$803.00
1
1mgIn Stock
$216.00
1
5mgIn Stock
$540.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

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    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

제품 설명 (Description)

GSPT1 degrader-15 (Compound Lib-B-15O) is a potent and highly selective GSPT1 molecular gel degrader, with a DC50 of 154 nM. GSPT1 degrader-15 has almost no effect on the expression of other proteins. GSPT1 degrader-15 exhibits significant anti-proliferative activity against leukemia cells and lymphoma cells. GSPT1 degrader-15 can be used in leukemia and lymphoma research [1].

References:
[1]. Li J, et al. A platform for the rapid synthesis of molecular glues (Rapid-Glue) under miniaturized conditions for direct biological screening. European journal of medicinal chemistry. 2023 Oct 5;258:115567.

제품 문서 (Product Documents)

Purity:>95.00%Appearance:A solid
COASDSData Sheet

화학적 특성 (Chemical Properties)

CAS 번호
3060504-66-4
분자식
C36H29N5O7S
분자량
675.71
용해도
DMSO: 100 mg/mL (147.99 mM; Need ultrasonic)
보관
Store at -20°C
배송 조건
평가용 샘플은 아이스팩과 함께 배송됩니다. 그 외 용량은 실온 배송되며, 요청 시 아이스팩과 함께 배송할 수 있습니다.

계산 도구 (Calculators)몰 농도 / 희석 / 분자량 / 단위 변환 / 생체 내 제형 / 용해도

g/mol

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