K67 |
| Catalog No.GC66004 |
K67은 특히 Keap1과 S349-인산화 p62 사이의 상호 작용을 억제합니다. 821d96072c2d58d8970e76f526b0f6b8K67은 p-p62가 Keap1과 Nrf2의 결합을 차단하는 것을 방지합니다. 821d96072c2d58d8970e76f526b0f6b8K67은 Keap1에 의해 구동되는 Nrf2의 유비퀴틴화 및 분해를 복원함으로써 높은 세포성 S351-인산화 p62로 HCC 배양물의 증식을 효과적으로 억제합니다.821d96072c2d58d8970e76f526b0f6b8
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2046250-48-8
Sample solution is provided at 25 µL, 10mM.
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K67 specifically inhibits the interaction between Keap1 and S349-phosphorylated p62. K67 prevents p-p62 from blocking the binding of Keap1 and Nrf2. K67 effectively inhibits the proliferation of HCC cultures with high cellular S351-phosphorylated p62 by restoring the ubiquitination and degradation of Nrf2 driven by Keap1[1].
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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