Leucinostatin A (Synonyms: P168) |
| Catalog No.GC44050 |
류시노스타틴 A(항생제 P168)는 특히 칸디다 알비칸스와 크립토코커스 네오포르만스에 대해 현저한 활성을 나타내는 노나펩티드입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 76600-38-9
Sample solution is provided at 25 µL, 10mM.
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Leucinostatin A is a fungal metabolite originally isolated from P. lilacinus with diverse biological activities. It is active against P. oryzae, B. cinera, P. chrysogenum, X. oryzae, S. cerevisiae, and C. albicans fungi and B. subtilis, S. aureus, S. lutea, and M. phlei bacteria in a disc assay. Leucinostatin A (0.1-1 μg/ml) reduces T cell activation induced by phorbol 12-myristate 13-acetate or an anti-CD3 antibody in a concentration-dependent manner. It inhibits proliferation of DU145 prostate cancer cells co-cultured with PrSC stromal cells in vitro (IC50 = 0.045 μg/ml).
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