Mitragynine-d3 is an analytical reference material intended for use as an internal standard for the quantification of mitragynine by GC- or LC-MS. Mitragynine is categorized as an opioid.1,2 Mitragynine and its derivatives have been identified in products sold as incense.3 This product is intended for research and forensic applications.
1.Matsumoto, K., Mizowaki, M., Suchitra, T., et al.Central antinociceptive effects of mitragynine in mice: Contribution of descending noradrenergic and serotonergic systemsEur. J. Pharmacol.317(1)75-81(1996) 2.Takayama, H., Ishikawa, H., Kurihara, M., et al.Studies on the synthesis and opioid agonistic activities of mitragynine-related indole alkaloids: Discovery of opioid agonists structurally different from other opioid ligandsJ. Med. Chem.45(9)1949-1956(2002) 3.Kikura-Hanajiri, R., Uchiyama, N., and Goda, Y.Survey of current trends in the abuse of psychotropic substances and plants in JapanLeg. Med. (Tokyo)13(3)109-115(2011)