NCR 631 is a 3-HAO inhibitor and 3-hydroxyanthranilic acid analogue. NCR-631 has anticonvulsant properties. NCR-631shows a concentration-dependent protective effect against the anoxia [1] [2].
References:
[1]. Luthman J. Anticonvulsant effects of the 3-hydroxyanthranilic acid dioxygenase inhibitor NCR-631. Amino Acids. 2000;19(1):325-34.
[2]. Luthman J, et al. Effects of the 3-hydroxyanthranilic acid analogue NCR-631 on anoxia-, IL-1 beta- and LPS-induced hippocampal pyramidal cell loss in vitro. Amino Acids. 1998;14(1-3):263-9.
References:
[1]. Luthman J. Anticonvulsant effects of the 3-hydroxyanthranilic acid dioxygenase inhibitor NCR-631. Amino Acids. 2000;19(1):325-34.
[2]. Luthman J, et al. Effects of the 3-hydroxyanthranilic acid analogue NCR-631 on anoxia-, IL-1 beta- and LPS-induced hippocampal pyramidal cell loss in vitro. Amino Acids. 1998;14(1-3):263-9.