GLPBio

Estrogen/progestogen Receptor

The estrogen/progestogen receptors are activated by the hormone estrogen/progesterone and regulate the gene transcription.

Products Related to Estrogen/progestogen Receptor(156)

  • GC18462 structure
    GC184623-Formylsalicylic Acid
    CAS: 610-04-8
    Purity: >98%

    3-Formylsalicylic acid is a non-competitive inhibitor of estrone sulfatase (IC50 = 150 nM; Ki = 120 nM), the enzyme that converts estrone sulfate to estrone.

  • GC18635 structure
    GC1863518-hydroxy-11-deoxy Corticosterone
    CAS: 379-68-0
    Purity: >98%

    18-hydroxy-11-deoxy Corticosterone (18-OH-DOC) is a mineralocorticoid secreted by the zona fasciculata of the adrenal gland.

  • GC18641 structure
    GC18641Ferutinin
    CAS: 41743-44-6
    Purity: >98.00%

    천연 테르페노이드 화합물인 페루티닌은 각각 33.1 nM 및 180.5 nM의 IC50을 갖는 에스트로겐 수용체 ERα 작용제 및 에스트로겐 ERβ-수용체 작용제/길항제입니다.

  • GC19552 structure
    GC195524-Hydroxyestradiol
    CAS: 5976-61-4
    Purity: >98.00%

    4-Hydroxyestradiol(4-Hydroxy-17β-estradiol)은 Estradiol의 내인성 대사 산물입니다. 4-Hydroxyestradiol은 발암성이며 유방 상피 세포에서 돌연변이 유발 활성을 나타냅니다. 4-Hydroxyestradiol은 0.48nM의 Ki로 경쟁 방식으로 Estradiol이 에스트로겐 수용체에 결합하는 것을 억제합니다.

  • GC25627 structure
    GC25627Menotropin
    CAS: 61489-71-2

    Menotropin is a gonadotropin drug extracted from the urine of postmenopausal women, containing follicle-stimulating hormone (FSH) and luteinizing hormone (LH).

  • GC25832 structure
    GC25832Raloxifene
    CAS: 84449-90-1
    Purity: >98%

    Raloxifene (Keoxifene, Pharoxifene, LY-139481, LY-156758, CCRIS-7129) is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women.

  • GC40241 structure
    GC40241Fulvestrant-d3
    Purity: >99.00%

    풀베스트란트-d3(ICI 182780-d3)은 풀베스트란트로 표시된 중수소입니다. 풀베스트란트(ICI 182780)는 순수한 항에스트로겐이며 IC50이 9.4nM인 강력한 에스트로겐 수용체(ER) 길항제입니다. 풀베스트란트는 또한 GPR30 작용제입니다. 풀베스트란트는 0.29nM의 IC50으로 ER-양성 MCF-7 세포의 성장을 효과적으로 억제합니다. 풀베스트란트는 또한 자가포식을 유도하고 항종양 효능이 있습니다.

  • GC40301 structure
    GC40301Tamoxifen N-oxide
    CAS: 75504-34-6
    Purity: >98.00%

    Tamoxifen is a selective estrogen receptor modulator that evokes tissue-dependent effects.

  • GC40833 structure
    GC40833(E/Z)-Endoxifen
    CAS: 110025-28-0
    Purity: >98.00%

    (E/Z)-Endoxifen is the most important active metabolite of tamoxifen (4-hydroxy-N-desmethyltamoxifen) and is an orally active nonsteroidal selective estrogen receptor modulator (SERM).

  • GC41266 structure
    GC41266Pregnanediol-3-Glucuronide
    CAS: 1852-49-9
    Purity: >95.00%

    프레그나네디올-3-글루쿠로나이드는 프로게스테론의 주요 말단 대사산물로 여성 월경 주기, 임신(임신 지원), 배발생 및 인간 및 기타 종의 모체 면역 반응과 같은 생리학적 과정에서 중요한 역할을 합니다.

  • GC41300 structure
    GC4130017β-hydroxy Exemestane
    CAS: 122370-91-6
    Purity: >98.00%

    17β-hydroxy Exemestane is the primary active metabolite of exemestane.

  • GC41671 structure
    GC41671(±)-Equol 4'-sulfate (sodium salt)
    CAS: 1189685-28-6
    Purity: >90.00%

    (±)-Equol 4'-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol.

  • GC41950 structure
    GC4195016α-hydroxy Estrone
    CAS: 566-76-7
    Purity: >99.50%

    16α-하이드록시 에스트론(16αOHE)은 주요 에스트라디올 대사 산물입니다.

  • GC42473 structure
    GC424734-tert-Octylphenol diethoxylate
    CAS: 2315-61-9
    Purity: >98.00%

    4-tert-Octylphenol diethoxylate is a degradation product of the multi-purpose surfactant, Triton X.

  • GC43629 structure
    GC43629Estradiol 3-sulfate 17β-Glucuronide (potassium salt)
    CAS: 10392-35-5
    Purity: >95.00%

    Estradiol 3-sulfate is a sulfated form of the steroid hormone 17β-estradiol, and is common in fetal plasma and in the breast tissues of patients with mammary carcinoma.

  • GC44036 structure
    GC44036Lasofoxifene
    CAS: 180916-16-9
    Purity: >98.00%

    라소폭시펜(CP-336156)은 경구 활성 및 선택적 에스트로겐 수용체 조절제(SERM)입니다.

  • GC44479 structure
    GC44479o,p'-DDE
    CAS: 3424-82-6
    Purity: >95.00%

    o,p'-DDE is a metabolite and degradation product of the organochlorine pesticide DDT.

  • GC44528 structure
    GC44528p,p'-DDT
    CAS: 50-29-3
    Purity: >98.00%

    p,p'-DDT is an organochlorine pesticide that induces 94.2% mortality of malaria mosquito (A.

  • GC44691 structure
    GC44691Progesterone 3-biotin
    Purity: >98.00%

    Progesterone, along with pregnenolone, is the biosynthetic precursor of all other steroid hormones.

  • GC44692 structure
    GC44692Progesterone 3-PEG11-biotin
    Purity: >98.00%

    Progesterone, along with pregnenolone, is the biosynthetic precursor of all other steroid hormones.

  • GC44693 structure
    GC44693Progesterone-3-biotinyl Photoaffinity Probe
    Purity: >95.00%

    Progesterone 3-biotinyl photoaffinity probe consists of active progesterone, a diazirine-UV (312 nm)-sensitive moiety, and a biotin tag.

  • GC45226 structure
    GC45226β-BHC
    CAS: 319-85-7
    Purity: 95.00%

    β-BHC is an isomer of the organochlorine pesticide γ-lindane that is a potential impurity found in commercial preparations of lindane.

  • GC45413 structure
    GC45413Cridanimod (sodium salt)
    CAS: 58880-43-6
    Purity: >98.00%

  • GC45450 structure
    GC45450Estriol-d2
    CAS: 53866-32-3
    Purity: >98.00%

    Etriol-d2는 Etriol이라고 표시된 중수소입니다. 에스트리올은 에스트로겐 수용체 음성 유방암 세포에서 G-단백질 결합 에스트로겐 수용체의 길항제입니다.