Small Interfering RNA (siRNA)

Lumasiran은 하이드록시산 산화효소 1(HAO1) mRNA를 표적으로 하는 특이적 siRNA 치료제이다.

Givosiran sodium은 hepatic aminolevulinate synthase 1 (ALAS1) messenger RNA를 표적으로 하는 작은 간섭 RNA이다.

HA2 peptide is a potent pH-responsive fusion peptide derived from hemagglutinin ( HA ), corresponding to the N-terminal fusion peptide domain consisting of 23 amino acid residues of HIV-1 gp41 envelope glycoprotein.

Lepodisiran (LY3819469) is a GalNAc-conjugated small interfering RNA lipid-lowering agent.

Mivelsiran (ALN-APP) sodium is an siRNA targeting the β-amyloid precursor protein ( APP ).

CGN peptide TFA is a 13 amino acid peptide composed of D-amino acids, referred to as CGN peptide.

Elebsiran scramble negative control is the scrambled sequence of Elebsiran, and its modification method is the same.

Vutrisiran sodium scrambled negative control is the sequence scrambled negative control of Vutrisiran sodium.

Adenosine-3',5'-bisphosphate ammonium is a XRN1 inhibitor ( IC 50 = 36 nM).

Etedesiran is a component of the AOC drug Delpacibart etedesiran, formed by the reaction of an siRNA that induces cleavage of mRNA encoding myotonic dystrophy protein kinase (MTPK or DMPK ) with SMCC linker.

Braxlosiran is a component of the AOC reagent Delpacibart braxlosiran, consisting of an siRNA targeting DUX4 (double homeobox protein) and SMCC linker.

Zilebesiran (AD-85481; ALN-AGT) sodium is a long-acting liver-targeted small interfering RNA (siRNA) antihypertensive agent.

GAPDH Positive Control siRNA (Human), a siRNA product, is a human GAPDH siRNA positive control.

GAPDH siRNA Positive Control (Mouse/Rat), a siRNA product, is a mouse/rat GAPDH siRNA positive control.