Apoptosis

Hydroxyproline (DL-Hydroxyproline) is a non-essential amino acid and one of the main components of collagenous tissues.

TLSC702 is a human glyoxalase I ( hGLO I ) inhibitor with an IC 50 of 2.0 μM.

BCS12 is a CAIX inhibitor.

SHMT2-IN-1 is a potent serine hydroxymethyltransferase 2 ( SHMT2 ) inhibitor with an IC 50 of 1.21 μM and a K D of 10.6 μM.

Momilactone B is an inhibitor of α-amylase and α-glucosidase, with an IC 50 of 146.85 μg/mL against Aspergillus oryzae α-amylase and an IC 50 of 612.03 μg/mL against Saccharomyces cerevisiae α-glucosidase.

2-Hydroxymelatonin is a major hydroxylated metabolite of Melatonin.

Flumethrin -d 5 (FCR 2769-d 5 ) is the deuterium labeled Flumethrin.

Urolithin A - 13 C 6 is the 13 C-labeled Urolithin A.

MKI-3 is a selective microtubule-associated serine/threonine kinase-like ( MASTL ) inhibitor with an IC 50 of 5.72 nM and a K d of 1.89 nM.

cis-V-11-0711 is the cis form of V-11-0711.

BI1071 is an orally active Nur77-Bcl-2 apoptotic pathway modulator.

DIM-3,5-Cl2 is an inverse NR4A1/NR4A2 agonist with K D values of 7.7 μM and 12.0 μM for NR4A1 and NR4A2, respectively.

(E)-FOBISIN101 is a 14-3-3 protein-protein interaction ( 14-3-3 protein-protein interaction ) inhibitor, with IC 50 values of 9.3 and 16.4 μM for disrupting the binding of 14-3-3ζ or 14-3-3γ to PRAS40, respectively.

3-Ethoxy-5,6-dibromosalicylaldehyde is an IRE1/ERN1 inhibitor, with an IC 50 of 0.12 μM, a K i of 71-88 nM, and a K d of 100 nM against the ribonuclease activity of hIRE1α, as well as an IC 50 of 4.8 μM against yeast Ire1.

HDAC11-IN-5 is a selective, potent and orally active HDAC11 inhibitor with an IC 50 of 0.021 μM.

4-Methoxycinnamic acid ethyl ester (Ethyl p-methoxycinnamate) is an orally active natural compound found.

Epibestatin hydrochloride is an epimer of Bestatin, a DPP4 inhibitor and protease inhibitor, with an IC 50 of 17 μM against DPP4.

ASO-4625 is a 20-nucleotide gapmer antisense oligonucleotide with a full phosphorothioate backbone and 2'-O-(2-methoxy) ethyl ribose modifications, which targets BCL2 mRNA and BCL2L1 mRNA.

Buforin IIb TFA (BF2-B TFA) is an anticancer peptide, as well as an Antibacterial and Antifungal agent.

G4232 is an immune-silent BCL2 antisense oligonucleotide that binds to BCL2 mRNA to induce target degradation and inhibit Bcl-2 protein translation.

Nivitol (UP302) is a natural phenolic compound discovered from Dianella ensifolia and also acts as a Tyrosinase inhibitor.

YJ1206 TFA is an orally active selective CDK12 / CDK13 PROTAC degrader.

CPTH2 -d 4 is the deuterated-labeled CPTH2.

Ciprofloxacin hydrochloride (Bay-09867 hydrochloride) is an orally active, blood-brain barrier permeable fluoroquinolone antibacterial agent.