GLPBio

Innate Immunity

Products Related to Innate Immunity(566)

  • GC44590 structure
    GC44590Pellitorine
    CAS: 18836-52-7
    Purity: >98.00%

    Pellitorine은 Piper nigrum의 뿌리에서 분리된 화합물입니다. Pellitorine은 HL60 및 MCT-7 세포주에 대해 강력한 세포독성 활성을 나타냅니다. Pellitorine은 암 질환 연구의 잠재력을 가지고 있습니다.

  • GC44633 structure
    GC44633Phosphatidylserines (bovine)
    CAS: 1446756-47-3
    Purity: >98.00%

    Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina.

  • GC44696 structure
    GC44696Prolyl-glycyl-proline Peptide
    Purity: >95.00%

    Proline-glycine-proline (PGP) is a tripeptide molecule and an established biomarker for chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF).

  • GC44794 structure
    GC44794Pyrrophenone
    CAS: 341973-06-6
    Purity: >99.50%

    피로페논은 IC50 값이 4.2nM인 강력하고 특이적인 세포질 포스포리파제 A2α(cPLA2α) 억제제입니다.

  • GC44802 structure
    GC44802R-8507
    CAS: 338773-13-0
    Purity: >98.00%

    R-8507 is a small molecule antagonist of the TNF-α type 1 receptor (TNF-αRI).

  • GC44818 structure
    GC44818Resolvin D4
    CAS: 1025684-60-9
    Purity: >95.00%

    Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid.

  • GC44820 structure
    GC44820Resveratrol-3-O-Sulfate (sodium salt)
    CAS: 858127-11-4
    Purity: >95.00%

    Resveratrol-3-O-sulfate(나트륨)는 Resveratrol의 대사 산물입니다.

  • GC44839 structure
    GC44839Ridaifen-B
    CAS: 886465-70-9
    Purity: >98.00%

    An analog of tamoxifen

  • GC44851 structure
    GC44851Rosiglitazone (potassium salt)
    CAS: 316371-84-3
    Purity: >98.00%

    Rosiglitazone(BRL 49653) 칼륨은 경구 활성 선택적 PPARγ입니다. 작용제(EC50: 60nM, Kd: 40nM).

  • GC44910 structure
    GC44910Sodium Hydrogen Sulfide (hydrate)
    CAS: 207683-19-0
    Purity: >68.00%

    Hydrogen sulfide (H2S) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals.

  • GC44919 structure
    GC44919SP 600125, negative control
    CAS: 54642-23-8
    Purity: >99.50%

    SP 600125 is a selective, cell-permeable, reversible inhibitor of JNK isoforms 1-3 with Ki values of 0.19 μM.

  • GC44930 structure
    GC44930Sphingosine (d14:1)
    CAS: 24558-60-9
    Purity: >98.00%

    스핑고신(d14:1)(테트라데카스핑-4-에닌)은 스핑고리피드로 강력한 PKC(단백질 키나제 C) 억제제입니다. 스핑고신(d14:1)은 sn-1,2-디아실글리세롤(DAG)/포르볼 에스테르와의 상호작용을 방지합니다.

  • GC44948 structure
    GC44948StA-IFN-1
    CAS: 300839-31-0
    Purity: >98.00%

    StA-IFN-1 is an inhibitor of the interferon (IFN) induction pathway with an IC50 value of 4.1 μM in a GFP reporter assay for IFN induction similar to TPCA-1, which specifically inhibits the IKKβ component of the IFN induction pathway.

  • GC44956 structure
    GC44956Streptochlorin
    CAS: 120191-51-7
    Purity: >98.00%

    Streptochlorin is a bacterial metabolite originally isolated from Streptomyces sp.

  • GC44999 structure
    GC44999Tauro-α-muricholic Acid (sodium salt)
    CAS: 2260905-08-4
    Purity: >95.00%

    Tauro-α-muricholic acid (TαMCA) is an antagonist of the farnesoid X receptor (FXR; IC50 = 28 μM) and a taurine-conjugated form of the murine-specific primary bile acid α-muricholic acid.

  • GC45004 structure
    GC45004TC 14012 (trifluoroacetate salt)
    Purity: >95.00%

    C-X-C chemokine receptor type 4 (CXCR4) is a receptor for the stromal cell-derived factor-1 which is designated as chemokine ligand 12 (CXCL12).

  • GC45012 structure
    GC45012Tenofovir diphosphate (sodium salt)
    Purity: >95.00%

    Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase (Kis = 0.022 and 1.55 μM for RNA and DNA, respectively) and hepatitis B virus (HBV) polymerase (Ki = 0.18 μM).

  • GC45030 structure
    GC45030TG6-129
    CAS: 1164464-14-5
    Purity: >98.00%

    TG6-129는 EP2 수용체의 선택적 길항제입니다.

  • GC45057 structure
    GC45057TIQ-A
    CAS: 420849-22-5
    Purity: >98.00%

    TIQ-A는 TNKS2에 대해 IC50이 24nM인 강력한 TNKS(폴리-ART, PARP) 억제제입니다.

  • GC45063 structure
    GC45063Toll-Like Receptor 7 Ligand II
    CAS: 226907-52-4
    Purity: >98.00%

    Toll-Like Receptor 7 Ligand II(CL-087)는 강력한 경구 활성 TLR7 작용제입니다.

  • GC45146 structure
    GC45146VIP (human, porcine, rat, ovine) (trifluoroacetate salt)
    Purity: >98.00%

    Vasoactive intestinal peptide (VIP) is a peptide that acts as a neurotransmitter and hormone.

  • GC45154 structure
    GC45154W140 (trifluoroacetate salt)
    CAS: 909725-64-0
    Purity: >95.00%

    Sphingosine-1-phosphate (S1P) is a bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.

  • GC45155 structure
    GC45155W146 (trifluoroacetate salt)
    CAS: 909725-62-8
    Purity: >95.00%

    W146 (trifluoroacetate salt)은 EC50 값이 398nM인 스핀 고신 1인산 수용체 1 (S1PR1)의 선택적 길항제이다.

  • GC45193 structure
    GC45193Z-YVAD-CMK (trifluoroacetate salt)
    Purity: >95.00%

    Z-YVAD-CMK is an inhibitor of caspase-1 and caspase-3.