GLPBio

Innate Immunity

Products Related to Innate Immunity(566)

  • GC42832 structure
    GC42832Arachidic Acid (sodium salt)
    CAS: 13257-34-6
    Purity: >95.00%

    Arachidic acid is a long-chain saturated fatty acid that has been found in peanut butter and anaerobic fungi.

  • GC42856 structure
    GC42856AS-605240 (potassium salt)
    Purity: >98.00%

    Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of PI at the three position to produce the second messengers PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3.

  • GC42877 structure
    GC42877AUY954
    CAS: 820240-77-5
    Purity: >98.00%

    AUY954 is an orally bioavailable and selective agonist of the sphingosine-1-phosphate receptor 1 (S1P1; EC50 = 1.2 nM for stimulating GTPγS binding to S1P1 in CHO cells).

  • GC42880 structure
    GC42880Avenanthramide-C methyl ester
    CAS: 955382-52-2
    Purity: >90.00%

    Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM).

  • GC42891 structure
    GC42891azido-FTY720
    CAS: 881914-35-8
    Purity: >98.00%

    Azido-FTY720은 FTY720의 광활성화 유사체입니다.

  • GC42897 structure
    GC42897BAY 61-3606 (hydrochloride)
    CAS: 1615197-10-8
    Purity: >98.00%

    BAY 61-3606 (hydrochloride) is a potent and selective inhibitor of Syk kinase with a K i value of 7.5nM.

  • GC42925 structure
    GC42925Berteroin
    CAS: 4430-42-6
    Purity: >95.00%

    자연적으로 발생하는 설포라판 유사체인 베르테로인(Berteroin)은 항전이제입니다.

  • GC42953 structure
    GC42953BMS 345541 (trifluoroacetate salt)
    Purity: >98.00%

    BMS 345541 is a cell permeable inhibitor of the IκB kinases IKKα and IKKβ (IC50s = 4 and 0.3 μM).

  • GC42954 structure
    GC42954BMS 470539 (hydrochloride)
    CAS: 2341796-82-3
    Purity: >99.50%

    BMS 470539 (hydrochloride)은 선택성이 높고 강력한 흑색소-1 수용체 (MC-1R) 작용제이다. cAMP 축적 시험에서 인간과 쥐 MC1R에 대한 EC50 값은 각각 16.8nM과 11.6nM이다.

  • GC43032 structure
    GC43032C16 Globotriaosylceramide (d18:1/16:0)
    CAS: 137896-85-6
    Purity: >98.00%

    C16 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from C16 lactosylceramide.

  • GC43049 structure
    GC43049C18 Globotriaosylceramide (d18:1/18:0)
    CAS: 69283-33-6
    Purity: >98.00%

    C18 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from lactosylceramide.

  • GC43077 structure
    GC43077C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))
    CAS: 151057-28-2
    Purity: >98.00%

    C24:1 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids.

  • GC43136 structure
    GC43136Campestanol
    CAS: 474-60-2
    Purity: >98.00%

    Campestanol은 식물성 식품에서 찾을 수 있는 식물성 스테롤입니다.

  • GC43176 structure
    GC43176CAY10575
    CAS: 916985-21-2
    Purity: >95.00%

    CAY10575(화합물 8)는 IC50이 0.075 μ인 IKK2 억제제입니다.

  • GC43181 structure
    GC43181CAY10597
    CAS: 916046-55-4
    Purity: >98.00%

    The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and CRTH2/DP2.

  • GC43239 structure
    GC43239Chk2 Inhibitor
    CAS: 724708-21-8
    Purity: >95.00%

    Chk2 억제제(화합물 1)는 Chk2 및 Chk1에 대한 IC50이 각각 13.5nM 및 220.4nM인 체크포인트 키나제 2(Chk2)의 강력하고 선택적인 억제제입니다. Chk2 억제제는 강한 ATM(ataxia telangiectasia mutated) 의존성 Chk2 매개 방사선 보호 효과를 유발할 수 있습니다.

  • GC43242 structure
    GC43242Chloramphenicol Succinate
    CAS: 3544-94-3
    Purity: >99.00%

    Chloramphenicol succinate is a water-soluble prodrug form of the antibiotic chloramphenicol.

  • GC43310 structure
    GC43310Corticostatin (human) (trifluoroacetate salt)
    Purity: >95.00%

    Corticostatin is a corticostatic peptide that has been found in human granulocytes.

  • GC43320 structure
    GC43320CPI-268456
    CAS: 1380087-86-4
    Purity: >98.00%

    CPI-268456(화합물 141)은 IC50이 < 0.5 μM인 강력한 BRD4 억제제입니다.

  • GC43325 structure
    GC43325Cromolyn (sodium salt hydrate)
    Purity: >98.00%

    Cromolyn is a chromone complex that acts as a mast cell stabilizer, preventing the release of histamine.

  • GC43328 structure
    GC43328C-Type Natriuretic Peptide-22 (human, porcine, rat) (trifluoroacetate salt)
    Purity: >95.00%

    C-Type natriuretic peptide-22 (CNP-22) is an endogenous peptide with diverse biological activities.

  • GC43340 structure
    GC43340Cyclic di-IMP (sodium salt)
    Purity: >95.00%

    Cyclic di-IMP (sodium salt) (c-di-IMP) is a synthetic second messenger structurally related to the bacterial second messengers cyclic di-GMP and cyclic di-AMP.

  • GC43395 structure
    GC43395Deethylindanomycin
    CAS: 106803-22-9
    Purity: >95.00%

    Deethylindanomycin is a polyether antibiotic that has been found in S.

  • GC43396 structure
    GC43396Defensin HNP-1 (human) (trifluoroacetate salt)
    Purity: >95.00%

    Defensin HNP-1 is a peptide secreted by polymorphonuclear leukocytes (PMNs) that has antimicrobial properties.