Obesity, Appetite Control & Diabetes
Obesity, Appetite Control & Diabetes
Satiety, appetite, and craving are CNS drives, whereas metabolism and energy utilization are peripheral endocrine actions.
Stephen M. Stahl, M.D., Ph.D. read more
Research Areas
Products Related to Obesity, Appetite Control & Diabetes(354)
- GC43754Ghrelin (rat) (trifluoroacetate salt)CAS: 659739-25-0Purity: >95.00%
Ghrelin is an endogenous gastrointestinal hormone and neuropeptide that binds to the growth hormone (GH) secretagogue receptor (GHS-R).
- GC43762GLP-1 (7-36) amide (trifluoroacetate salt)Purity: >98.00%
GLP-1 (7-36) amide is a peptide hormone released from intestinal L-cells upon nutrient consumption.
- GC43763GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat) (trifluoroacetate salt)Purity: >95.00%
Glucagon-like peptide-1 (GLP-1) (7-37) is an endogenous incretin hormone and truncated form of GLP-1 (1-37) that is produced via cleavage of preproglucagon in the pancreas and intestine.
- GC43764GLP-2 (human) (trifluoroacetate salt)Purity: >95.00%
Glucagon-like peptide-2 (GLP-2) is an endogenous peptide hormone formed in L cells of the small and large intestine by cleavage of proglucagon in response to nutrient ingestion.
- GC43766Glucagon Receptor Antagonist Inactive ControlCAS: 362482-00-6Purity: >95.00%
An inactive control for glucagon receptor antagonist I
- GC43768Glucocerebrosides (Gaucher's spleen)CAS: 85305-87-9Purity: >98.00%
Glucocerebrosides are formed by the tethering of glucose to a ceramide by glucosylceramide synthase.
- GC43773Glyburide (potassium salt)CAS: 52169-36-5Purity: >98.00%
Glyburide is a sulfonylurea and an inhibitor of sulfonylurea receptor 1 (SUR1) linked to ATP-sensitive potassium channel Kir6.2 (IC50 = 4.3 nM).
- GC43778Glycolithocholic AcidCAS: 474-74-8Purity: >98.00%
Glycolithocholic Acid은 2차 담즙산과 글리신의 결합체로 체내에서 생성되는 내원성 대사 산물이다.
- GC43779Glycolithocholic Acid (sodium salt)CAS: 24404-83-9Purity: >95.00%
Glycolithocholic acid is a glycine conjugate of lithocholic acid, a bile acid.
- GC43803HA-1077 (hydrochloride)CAS: 203911-27-7Purity: >98.00%
Fasudil (HA-1077; AT877) 디 하이드로 클로라이드는 비특이적 rhoA/암석 억제제이며 또한 단백질 키나제에 대한 억제 효과가 있으며, 0.33 &7##8886; m 0.158&777###956; offlineefficient_models_2022q2.md;M, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively.en_ko_2021q1.mdHA-1077 (hydrochloride) is also a potent Ca2+ channel antagonist and vasodilator.en_ko_2021q1.md
- GC44077Lithocholic Acid 3-sulfate (sodium salt)CAS: 64936-81-8Purity: >98.00%
Lithocholic acid 3-sulfate is a metabolite of the secondary bile acid lithocholic acid.
- GC44226MLS-0322825 Cmpd 23CAS: 1908414-82-3Purity: >98.00%
MLS-0322825 Cmpd 23은 IC50이 0.8 μ인 저분자량 단백질 티로신 포스파타제(LMPTP)의 선택적 억제제입니다.
- GC44300N-Acetylagmatine (acetate salt)Purity: >95.00%
Agmatine is a natural polyamine formed by the enzymatic decarboxylation of arginine.
- GC44377Neuromedin S (human) (trifluoroacetate salt)Purity: >95.00%
Neuromedin S is a neuropeptide expressed in brain.
- GC44441N-Oleoyl LeucineCAS: 136560-76-4Purity: >98.00%
N-Oleoyl Leucine is a fatty acid–amino acid conjugate (FAAA) that belongs to the family of N-acyl amino acids.
- GC44484Obestatin (rat) (trifluoroacetate salt)Purity: >95.00%
Obestatin is a 23-amino acid peptide hormone that is formed by cleavage of the ghrelin and obestatin prepropeptide.
- GC44516Orlistat Degradation Product (sodium salt)Purity: >95.00%
Orlistat degradation product is a degradation product of the digestive lipase inhibitor orlistat.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC43754 | Ghrelin (rat) (trifluoroacetate salt) | 659739-25-0 | >95.00% | |
Ghrelin is an endogenous gastrointestinal hormone and neuropeptide that binds to the growth hormone (GH) secretagogue receptor (GHS-R). | ||||
| GC43762 | GLP-1 (7-36) amide (trifluoroacetate salt) | - | >98.00% | |
GLP-1 (7-36) amide is a peptide hormone released from intestinal L-cells upon nutrient consumption. | ||||
| GC43763 | GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat) (trifluoroacetate salt) | - | >95.00% | |
Glucagon-like peptide-1 (GLP-1) (7-37) is an endogenous incretin hormone and truncated form of GLP-1 (1-37) that is produced via cleavage of preproglucagon in the pancreas and intestine. | ||||
| GC43764 | GLP-2 (human) (trifluoroacetate salt) | - | >95.00% | |
Glucagon-like peptide-2 (GLP-2) is an endogenous peptide hormone formed in L cells of the small and large intestine by cleavage of proglucagon in response to nutrient ingestion. | ||||
| GC43766 | Glucagon Receptor Antagonist Inactive Control | 362482-00-6 | >95.00% | |
An inactive control for glucagon receptor antagonist I | ||||
| GC43768 | Glucocerebrosides (Gaucher's spleen) | 85305-87-9 | >98.00% | |
Glucocerebrosides are formed by the tethering of glucose to a ceramide by glucosylceramide synthase. | ||||
| GC43773 | Glyburide (potassium salt) | 52169-36-5 | >98.00% | |
Glyburide is a sulfonylurea and an inhibitor of sulfonylurea receptor 1 (SUR1) linked to ATP-sensitive potassium channel Kir6.2 (IC50 = 4.3 nM). | ||||
| GC43778 | Glycolithocholic Acid | 474-74-8 | >98.00% | |
Glycolithocholic Acid은 2차 담즙산과 글리신의 결합체로 체내에서 생성되는 내원성 대사 산물이다. | ||||
| GC43779 | Glycolithocholic Acid (sodium salt) | 24404-83-9 | >95.00% | |
Glycolithocholic acid is a glycine conjugate of lithocholic acid, a bile acid. | ||||
| GC43800 | GW 9578 | 247923-29-1 | >98.00% | |
GW9578은 강력한 지질 저하 활성을 가진 아형 선택적 PPARα 작용제(쥐와 인간 PPAR-α의 경우 EC50이 5 및 50nM)입니다. | ||||
| GC43803 | HA-1077 (hydrochloride) | 203911-27-7 | >98.00% | |
Fasudil (HA-1077; AT877) 디 하이드로 클로라이드는 비특이적 rhoA/암석 억제제이며 또한 단백질 키나제에 대한 억제 효과가 있으며, 0.33 &7##8886; m 0.158&777###956; offlineefficient_models_2022q2.md;M, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively.en_ko_2021q1.mdHA-1077 (hydrochloride) is also a potent Ca2+ channel antagonist and vasodilator.en_ko_2021q1.md | ||||
| GC43929 | JMV3002 | 925239-03-8 | >98.00% | |
Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor that stimulates food intake and transduces signals to hypothalamic regulatory nuclei that control energy homeostasis. | ||||
| GC44024 | Lactisole | 150436-68-3 | >98.00% | |
Lactisole은 전형적인 단맛 수용체 길항제로 선택적으로 T1R3 아단위를 표적으로 한다. | ||||
| GC44077 | Lithocholic Acid 3-sulfate (sodium salt) | 64936-81-8 | >98.00% | |
Lithocholic acid 3-sulfate is a metabolite of the secondary bile acid lithocholic acid. | ||||
| GC44191 | MHY908 | 1393371-39-5 | >98.00% | |
MHY908은 PPARα와 PPARγ의 강력한 이중 작용제입니다. | ||||
| GC44221 | ML-262 | 902502-82-3 | >95.00% | |
ML-262 is an inhibitor of hepatic lipid droplet formation (IC50 = 6.4 nM in murine AML-12 cells), which is associated with non-alcoholic fatty liver disease. | ||||
| GC44226 | MLS-0322825 Cmpd 23 | 1908414-82-3 | >98.00% | |
MLS-0322825 Cmpd 23은 IC50이 0.8 μ인 저분자량 단백질 티로신 포스파타제(LMPTP)의 선택적 억제제입니다. | ||||
| GC44300 | N-Acetylagmatine (acetate salt) | - | >95.00% | |
Agmatine is a natural polyamine formed by the enzymatic decarboxylation of arginine. | ||||
| GC44341 | ND-336 | 1807453-83-3 | >95.00% | |
ND-336은 매트릭스 메탈로프로테이나제(MMP)-2, MMP-9 및 MMP-14의 선택적 억제제이며 Kis는 각각 85, 150 및 120nM입니다. | ||||
| GC44377 | Neuromedin S (human) (trifluoroacetate salt) | - | >95.00% | |
Neuromedin S is a neuropeptide expressed in brain. | ||||
| GC44441 | N-Oleoyl Leucine | 136560-76-4 | >98.00% | |
N-Oleoyl Leucine is a fatty acid–amino acid conjugate (FAAA) that belongs to the family of N-acyl amino acids. | ||||
| GC44481 | O-7460 | 1572051-31-0 | >95.00% | |
O-7460은 IC50이 0.69μM인 강력하고 선택적인 DAGLα 억제제입니다. | ||||
| GC44484 | Obestatin (rat) (trifluoroacetate salt) | - | >95.00% | |
Obestatin is a 23-amino acid peptide hormone that is formed by cleavage of the ghrelin and obestatin prepropeptide. | ||||
| GC44516 | Orlistat Degradation Product (sodium salt) | - | >95.00% | |
Orlistat degradation product is a degradation product of the digestive lipase inhibitor orlistat. | ||||