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DDR1/DDR2 Receptor

DDR1/DDR2 receptors are unique receptor tyrosine kinases that bind to collagen and activated in several signaling pathways, including Shp-2, Src and MAPK. They have been associated with diseases like fibrosis, atherosclerosis and cancer.

Products Related to DDR1/DDR2 Receptor(1)

  • GC17365 structure
    GC17365DDR1-IN-1
    CAS: 1449685-96-4
    Purity: >98.00%

    DDR1-IN-1은 IC50이 105nM인 강력하고 선택적인 DDR1 수용체 티로신 키나제 억제제입니다. DDR2의 경우 4배 덜 강력합니다(IC50 = 413nM).