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홈 >> Signaling Pathways >> Tyrosine Kinase >> Tie-2

Tie-2

Tie-2 (angiopoietin receptor) is a receptor tyrosine kinase and is capable of physiologic activation as a result of binding the angiopoietins.

Products for  Tie-2

  1. Cat.No. 상품명 정보
  2. GC13598 MGCD-265 MGCD-265는 각각 29nM 및 10nM의 IC50을 갖는 c-Met 및 VEGFR2 티로신 키나제의 강력한 경구 활성 억제제입니다. MGCD-265는 상당한 항종양 활성을 가지고 있습니다. MGCD-265 Chemical Structure
  3. GC49686 N-desmethyl Regorafenib N-oxide An active metabolite of regorafenib N-desmethyl Regorafenib N-oxide Chemical Structure
  4. GC44474 NVP-AEW541 (hydrochloride) Insulin-like growth factor 1 receptor (IGF-1R) is a receptor tyrosine kinase whose activation leads to angiogenesis as well as cell proliferation, survival, transformation, and metastasis. NVP-AEW541 (hydrochloride) Chemical Structure
  5. GC14898 Tie2 kinase inhibitor

    Tunica Interna Endothelial Cell Kinase 2 Inhibitor

     Tie2 kinase inhibitor는 Tie2를 선택적으로 억제하는 되돌릴 수 있는 억제제로 IC50가 250 nM이다. Tie2 kinase inhibitor Chemical Structure

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