Tie-2
Tie-2 (angiopoietin receptor) is a receptor tyrosine kinase and is capable of physiologic activation as a result of binding the angiopoietins.
Products Related to Tie-2 (4)
- GC14898Tie2 kinase inhibitorCAS: 948557-43-5Purity: >99.00%
Tie2 kinase inhibitor는 Tie2를 선택적으로 억제하는 되돌릴 수 있는 억제제로 IC50가 250 nM이다.
- GC44474NVP-AEW541 (hydrochloride)CAS: 2320261-63-8Purity: >98.00%
Insulin-like growth factor 1 receptor (IGF-1R) is a receptor tyrosine kinase whose activation leads to angiogenesis as well as cell proliferation, survival, transformation, and metastasis.
- GC49686N-desmethyl Regorafenib N-oxideCAS: 835621-12-0Purity: >90.00%
An active metabolite of regorafenib
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC13598 | MGCD-265 | 875337-44-3 | >98.50% | |
MGCD-265는 각각 29nM 및 10nM의 IC50을 갖는 c-Met 및 VEGFR2 티로신 키나제의 강력한 경구 활성 억제제입니다. MGCD-265는 상당한 항종양 활성을 가지고 있습니다. | ||||
| GC14898 | Tie2 kinase inhibitor | 948557-43-5 | >99.00% | |
Tie2 kinase inhibitor는 Tie2를 선택적으로 억제하는 되돌릴 수 있는 억제제로 IC50가 250 nM이다. | ||||
| GC44474 | NVP-AEW541 (hydrochloride) | 2320261-63-8 | >98.00% | |
Insulin-like growth factor 1 receptor (IGF-1R) is a receptor tyrosine kinase whose activation leads to angiogenesis as well as cell proliferation, survival, transformation, and metastasis. | ||||
| GC49686 | N-desmethyl Regorafenib N-oxide | 835621-12-0 | >90.00% | |
An active metabolite of regorafenib | ||||