Rupintrivir (Synonyms: AG7088) |
Catalog No.GC50441 |
항바이러스 약물인 Rupintrivirvr(AG7088)은 인간 리노바이러스(HRV) 3C 프로테아제의 강력하고 선택적이고 비가역적인 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 223537-30-2
Sample solution is provided at 25 µL, 10mM.
Potent and selective irreversible human rhinovirus (HRV) 3C protease inhibitor (EC50 = 5 nM). Exhibits no significant inhibition against a variety of serine and cysteine proteases. Inhibits replication of a panel of 48 different HRV serotypes in H1-HeLA and MRC-5 cell protection assays. products are for biomedical research use only. They are not intended for human or veterinary use.
Patick et al (1999) In vitro antiviral activity of AG7088, a potent inhibitor of human rhinovirus 3C protease. Antimicrob.Agents Chemother. 43 2444 PMID:10508022 |Dragovich et al (1999) Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 3. Structure-activity studies of ketomethylene-containing peptidomimetics. J.Med.Chem. 42 1203 PMID:10197964
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