(S)-5-Acetamido-2-aminopentanoic acid is an adamantane-labeled glutamine analog [1].
In Vitro, (S)-5-Acetamido-2-aminopentanoic acid (compound 7) (1 mM; 20 min) does not function as a valid glutamine analog in U87/EGFRvIII cells, as it lacks temperature-dependent active transport and glutamine-dependent competitive uptake[1].
References:
[1]. Xue M, et al. Supramolecular Probes for Assessing Glutamine Uptake Enable Semi-Quantitative Metabolic Models in Single Cells. J Am Chem Soc. 2016;138(9):3085-3093.
In Vitro, (S)-5-Acetamido-2-aminopentanoic acid (compound 7) (1 mM; 20 min) does not function as a valid glutamine analog in U87/EGFRvIII cells, as it lacks temperature-dependent active transport and glutamine-dependent competitive uptake[1].
References:
[1]. Xue M, et al. Supramolecular Probes for Assessing Glutamine Uptake Enable Semi-Quantitative Metabolic Models in Single Cells. J Am Chem Soc. 2016;138(9):3085-3093.