GLPBio

KRAS G12D inhibitor 10

Catalog No.: GC83345Purity:>88.50%
COASDSData Sheet
KRAS G12D inhibitor 10 is a potent inhibitor of KRAS G12D.

Products are for research use only. Not for human use. We do not sell to patients.

KRAS G12D inhibitor 10
Cas No.: 2648551-54-4
10mM (in 1mL DMSO)In Stock
$416.00
1
1mgIn Stock
$122.00
1
5mgIn Stock
$306.00
1
10mgIn Stock
$497.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

KRAS G12D inhibitor 10 is a potent inhibitor of KRAS G12D. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12D inhibitor 10 has the potential for the research of KRAS G12D-mediated cancer (extracted from patent WO2021108683A1, compound 34) [1].

References:
[1]. Jennifer PITZEN, et al. Covalent ras inhibitors and uses thereof. Patent WO2021108683A1.

Product Documents

Purity:>88.50%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
2648551-54-4
Molecular Formula
C33H41ClN8O2
Molecular Weight
617.18
Solubility
DMSO: 100 mg/mL (162.03 mM; Need ultrasonic)
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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